null

SMILES Oc1ccc(cc1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2cc(O)ccc2CC1

InChI Key InChIKey=KMPCNSDMKUQNHK-SANMLTNESA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50505996   

TargetEstrogen receptor(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50505996(CHEMBL4533966 | US11149031, Example 2)copy SMILEScopy InChI
Affinity DataEC50:  0.300nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154MB3PubMed
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))TBA
LigandPNGBDBM50505996(CHEMBL4533966 | US11149031, Example 2)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NZ8BT3US Patent
TargetEstrogen receptor [298-554,D538G](Homo sapiens (Human))TBA
LigandPNGBDBM50505996(CHEMBL4533966 | US11149031, Example 2)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NZ8BT3US Patent
TargetEstrogen receptor [298-554](Homo sapiens (Human))TBA
LigandPNGBDBM50505996(CHEMBL4533966 | US11149031, Example 2)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NZ8BT3US Patent