null
SMILES COc1cc(cc(n1)-c1ccc(cc1)C(O)=O)C(=O)N1CCC2(CC1)Cc1cnn(C(C)C)c1C(=O)C2
InChI Key InChIKey=LXZMHBHEXAELHH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 29 hits for monomerid = 50511112
Affinity DataIC50: 31nMAssay Description:Inhibition of ACC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human ACC1 using acetyl coA as substrate incubated for 1 hr by transcreener fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition of human BSEP expressed in baculovirus infected Hi5 insect cells in presence of taurocholic acid by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human SLC22A2 expressed in HEK293 cells in presence of para-aminohippuric acid/metforminMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human SLC22A8 expressed in HEK293 cells in presence of para-aminohippuric acid/metforminMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human SLC22A6 expressed in HEK293 cells in presence of para-aminohippuric acid/metforminMore data for this Ligand-Target Pair
Affinity DataIC50: 1.37E+5nMAssay Description:Inhibition of human OATP1B3 expressed in HEK293 cells n presence of rosuvastatinMore data for this Ligand-Target Pair
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of human OATP1B1 expressed in HEK293 cells n presence of rosuvastatinMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of human ABCG2 expressed in MDCK2-LE cells in presence of digoxinMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of human ABCC1 expressed in MDCK2-LE cells in presence of pitavastatinMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of UGT2B15 in human liver microsomes in presence of UDPGA by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of UGT2B7 in human liver microsomes incubated for 60 mins in presence of UDPGA by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of UGT1A9 in human liver microsomes incubated for 30 mins in presence of UDPGA by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of UGT1A6 in human liver microsomes incubated for 90 mins in presence of UDPGA by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:inhibition of CYP2B6 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:inhibition of CYP2C8 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of UGT1A4 in human liver microsomes incubated for 30 mins in presence of UDPGA by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Inhibition of rat ACC1 using acetyl-CoA as substrate incubated for 20 mins in presence of [14C]O3 by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70nMAssay Description:Uncompetitive inhibition of human ACC2 incubated for 15 mins in presence of ATP by Line weaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Uncompetitive inhibition of human ACC1 incubated for 15 mins in presence of ATP by Line weaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human ACC2 using acetyl coA as substrate incubated for 1 hr by transcreener fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human ACC2 using acetyl coA as substrate incubated for 1 hr by transcreener fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human ACC1 using acetyl coA as substrate incubated for 1 hr by transcreener fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of ACC2 (unknown origin)More data for this Ligand-Target Pair