null
SMILES CC(C)CNC(=O)n1c2ccc(cc2oc1=O)C1CCN(C)CC1
InChI Key InChIKey=AYXQGWOLRJUITD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50511298
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of Illinois at Chicago
Curated by ChEMBL
University of Illinois at Chicago
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human NAAA expressed in HEK293 cells using PAMCA as fluorogenic substrate preincubated for 30 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Affinity DataEC50: 410nMAssay Description:Inhibition of acid ceramidase in Krabbe's disease patient-derived primary fibroblasts using Rbm14-12 as substrate measured after 2 hrs by fluorescenc...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University of Illinois at Chicago
Curated by ChEMBL
University of Illinois at Chicago
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of human FAAH expressed in HEK293 cells using AMC arachidonyl amide as fluorogenic substrate preincubated for 50 mins followed by substrat...More data for this Ligand-Target Pair
Affinity DataKon: 0.00250M-1s-1Assay Description:Time-dependent inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 166nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair