null

SMILES Clc1ccc(Nc2cn[nH]n2)cc1

InChI Key InChIKey=IUTZKZLVPUPHDA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50530532   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SIB Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50530532(CHEMBL4443463)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of full-length human IDO1 expressed in Escherichia coli Rosetta (DE3) using L-Trp substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2KK8PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SIB Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50530532(CHEMBL4443463)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of IDO1 (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2KK8PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SIB Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50530532(CHEMBL4443463)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of full-length human IDO1 expressed in Escherichia coli Rosetta (DE3) using L-Trp substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2KK8PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SIB Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50530532(CHEMBL4443463)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of IDO1 (unknown origin) by enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2KK8PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SIB Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50530532(CHEMBL4443463)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of IDO1 (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2KK8PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SIB Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50530532(CHEMBL4443463)copy SMILEScopy InChI
Affinity DataIC50: 23nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9G4FPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SIB Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50530532(CHEMBL4443463)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells incubated for 48 hrs using L-tryptophan as substrate by absorbance methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D010NPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SIB Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50530532(CHEMBL4443463)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Inhibition of human IDO1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D010NPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SIB Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50530532(CHEMBL4443463)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged IDO1 (1 to 403 residues) expressed in Escherichia coli BL21 using L-tryptophan as substrate pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D010NPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SIB Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50530532(CHEMBL4443463)copy SMILEScopy InChI
Affinity DataKd:  2.30E+3nMAssay Description:Binding affinity to recombinant human IDO1 expressed in Escherichia coli BL21 incubated for 4 hrs by UV-Visible SpectroscopyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D010NPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SIB Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50530532(CHEMBL4443463)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9G4FPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SIB Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50530532(CHEMBL4443463)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of IDO1 (unknown origin) by enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2KK8PubMed