null

SMILES CCC(Nc1ccc(cc1Cl)S(=O)(=O)Nc1nccs1)c1ccccc1

InChI Key InChIKey=SDPRTZGVTOHKRX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50530538   

TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50530538(CHEMBL4580815)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32344PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50530538(CHEMBL4580815)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32344PubMed
TargetSodium channel protein type 1 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50530538(CHEMBL4580815)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of recombinant human full length Nav1.1 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32344PubMed
TargetSodium channel protein type 5 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50530538(CHEMBL4580815)copy SMILEScopy InChI
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of recombinant human full length Nav1.5 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -60 mV holding potential b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32344PubMed
TargetSodium channel protein type 5 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50530538(CHEMBL4580815)copy SMILEScopy InChI
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of recombinant human full length Nav1.5 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -60 mV holding potential b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32344PubMed
TargetSodium channel protein type 1 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50530538(CHEMBL4580815)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of recombinant human full length Nav1.1 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32344PubMed