null

SMILES CS(=O)(=O)Nc1cccc(c1)N1CC[C@](O)(C(=O)NCc2cc(F)cc(Cl)c2)C1=O

InChI Key InChIKey=JASKJMAKHABJJZ-IBGZPJMESA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50531154   

TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50531154(CHEMBL4448427)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of MetAP2 in HUVEC assessed as reduction in viability incubated for 3 days by CyQUANT Direct Cell proliferation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4MXQPubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50531154(CHEMBL4448427)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal MetAP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4MXQPubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50531154(CHEMBL4448427)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and MnCl2 as co-facor preincubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4MXQPubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50531154(CHEMBL4448427)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and MnCl2 as co-facor preincubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4MXQPubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50531154(CHEMBL4448427)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of MetAP2 in HUVEC assessed as reduction in viability incubated for 3 days by CyQUANT Direct Cell proliferation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4MXQPubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50531154(CHEMBL4448427)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal MetAP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4MXQPubMed