null

SMILES COc1cc(Nc2ccnc3ccc(cc23)C(C)(C)C)cc(OC)c1OC

InChI Key InChIKey=FPWOHBGDJPLADA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50537132   

TargetSerine/threonine-protein kinase NLK(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50537132(CHEMBL530635 | TCMDC-138886)copy SMILEScopy InChI
Affinity DataKd:  350nMAssay Description:Binding affinity to biotinylated full length human NLK expressed in Escherichia coli incubated for 1.5 hrs by fluorescent tracer dependent TR-FRET ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28919C7PubMed
TargetCyclin-G-associated kinase(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50537132(CHEMBL530635 | TCMDC-138886)copy SMILEScopy InChI
Affinity DataKd:  25nMAssay Description:Binding affinity to biotinylated human GAK (13 to 338 residues) expressed in Escherichia coli incubated for 1.5 hrs by fluorescent tracer dependent T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28919C7PubMed
TargetCyclin-G-associated kinase(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50537132(CHEMBL530635 | TCMDC-138886)copy SMILEScopy InChI
Affinity DataKd:  34nMAssay Description:Binding affinity to human wild type partial length GAK (G13 to Y338 residues) expressed in bacterial expression system by KinomeScan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9FC5PubMed
TargetAtypical kinase COQ8A, mitochondrial(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50537132(CHEMBL530635 | TCMDC-138886)copy SMILEScopy InChI
Affinity DataKd:  740nMAssay Description:Binding affinity to biotinylated full length human ADCK3 expressed in Escherichia coli incubated for 1.5 hrs by fluorescent tracer dependent TR-FRET ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28919C7PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50537132(CHEMBL530635 | TCMDC-138886)copy SMILEScopy InChI
Affinity DataKd:  670nMAssay Description:Binding affinity to biotinylated human RIPK2 (1 to 310 residues) expressed in Escherichia coli incubated for 1.5 hrs by fluorescent tracer dependent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28919C7PubMed