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SMILES CC(O)CN1[C@@H](C)CN(CCSC(c2ccc(F)cc2)c2ccc(F)cc2)C[C@H]1C
InChI Key InChIKey=GVCYHQGCEQPNRF-DFNIBXOVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50540131
Affinity DataKi: 5.60nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Displacement of [3H]-(+)-pentazocine from Sigma1 receptor in guinea pig cortex membranes incubated for 120 mins by microbeta scintillation counting m...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute on Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum membranes incubated for 120 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute on Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatal membranes incubated for 120 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
National Institute on Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute on Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 58nMAssay Description:Displacement of [3H]WIN35428 from DAT (unknown origin) transiently expressed in COS7 cells incubated for > 90 mins by beta scintillation counting met...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
National Institute on Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute on Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of human DAT transiently expressed in COS7 cells assessed as reduction in [3H]-DA uptake measured after 5 mins by beta-scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 1.47E+3nMAssay Description:Displacement of [3H]-N-methylspiperone from human D3 receptor expressed in HEK293 cell membranes measured after 60 mins by microbeta scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 1.19E+4nMAssay Description:Displacement of [3H]-N-methylspiperone from human D2L receptor expressed in HEK293 cell membranes measured after 60 mins by microbeta scintillation c...More data for this Ligand-Target Pair
Affinity DataKi: 1.48E+4nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat midbrain membranes incubated for 60 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.48E+4nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat midbrain membranes incubated for 60 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
National Institute on Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute on Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataIC50: 635nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair