null

SMILES [2H]C([2H])([2H])Oc1cc(F)cc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50547305   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))TBA
LigandPNGBDBM50547305(CHEMBL4761695)copy SMILES
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]nisoxetine from recombinant human Dopamine transporter after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6WTXPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))TBA
LigandPNGBDBM50547305(CHEMBL4761695)copy SMILES
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50547305(CHEMBL4761695)copy SMILES
Affinity DataEC50:  990nMAssay Description:Positive allosteric modulation of rat mGlu7 expressed in HEK293 cells co- expressing GIRK assessed as potentiation of L-AP4-induced thallium flux inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6WTXPubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50547305(CHEMBL4761695)copy SMILES
Affinity DataEC50:  1.00E+3nMAssay Description:Positive allosteric modulation of rat mGlu7 expressed in HEK293 cells co- expressing GIRK assessed as potentiation of L-AP4-induced thallium flux inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6WTXPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50547305(CHEMBL4761695)copy SMILES
Affinity DataIC50: 3.50E+3nMAssay Description:Displacement of [3H]-Pentazocine from human recombinant sigma 1 receptor incubated for 120 mins by scintillation counting analysis relative to contro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6WTXPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50547305(CHEMBL4761695)copy SMILES
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of mGlu1 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6WTXPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50547305(CHEMBL4761695)copy SMILES
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of mGlu2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6WTXPubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))TBA
LigandPNGBDBM50547305(CHEMBL4761695)copy SMILES
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of mGlu3 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6WTXPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))TBA
LigandPNGBDBM50547305(CHEMBL4761695)copy SMILES
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of mGlu5 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6WTXPubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547305(CHEMBL4761695)copy SMILES
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of mGlu4 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6WTXPubMed
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50547305(CHEMBL4761695)copy SMILES
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGlu8 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6WTXPubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50547305(CHEMBL4761695)copy SMILES
Affinity DataEC50:  1.60E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547305(CHEMBL4761695)copy SMILES
Affinity DataEC50:  1.60E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM50547305(CHEMBL4761695)copy SMILES
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50547305(CHEMBL4761695)copy SMILES
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50547305(CHEMBL4761695)copy SMILES
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50547305(CHEMBL4761695)copy SMILES
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))TBA
LigandPNGBDBM50547305(CHEMBL4761695)copy SMILES
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50547305(CHEMBL4761695)copy SMILES
Affinity DataEC50:  1.10E+3nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6WTXPubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50547305(CHEMBL4761695)copy SMILES
Affinity DataEC50:  1.10E+3nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6WTXPubMed