null

SMILES CC(C)Oc1cc(F)cc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50547309   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))TBA
LigandPNGBDBM50547309(CHEMBL4753189)copy SMILES
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]nisoxetine from recombinant human Dopamine transporter after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6WTXPubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50547309(CHEMBL4753189)copy SMILES
Affinity DataEC50:  690nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6WTXPubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50547309(CHEMBL4753189)copy SMILES
Affinity DataEC50:  759nMAssay Description:Positive allosteric modulation of rat mGlu7 expressed in HEK293 cells co- expressing GIRK assessed as potentiation of L-AP4-induced thallium flux inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6WTXPubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50547309(CHEMBL4753189)copy SMILES
Affinity DataEC50:  690nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6WTXPubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50547309(CHEMBL4753189)copy SMILES
Affinity DataEC50:  750nMAssay Description:Positive allosteric modulation of rat mGlu7 expressed in HEK293 cells co- expressing GIRK assessed as potentiation of L-AP4-induced thallium flux inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6WTXPubMed