null

SMILES O=C(Nc1c2CCCc2cc2CCCc12)NS(=O)(=O)\C=C\c1nccs1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50547438   

LigandPNGBDBM50547438(CHEMBL4752523)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NLRP3 (unknown origin) assessed as inhibition of TNFalpha production by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547438(CHEMBL4752523)copy SMILES
Affinity DataIC50: 33nMAssay Description:Inhibition of NLRP3 (unknown origin) assessed as inhibition of IL-18 production by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547438(CHEMBL4752523)copy SMILES
Affinity DataIC50: 35nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547438(CHEMBL4752523)copy SMILES
Affinity DataIC50: 26nMAssay Description:Inhibition of NLRP3 inflammasome activation in human THP1 cells assessed as inhibition of IL-1beta release in presence of nigericinMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547438(CHEMBL4752523)copy SMILES
Affinity DataIC50: 24nMAssay Description:Inhibition of NLRP3 inflammasome activation in human THP1 cells assessed as inhibition of IL-1beta release in presence of MSUMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed