null

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc3oc(cc3c2)C(=O)c2cc3cc(O)ccc3[nH]2)no1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50551644   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50551644(CHEMBL4745937)copy SMILES
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human FLT3 ITD mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KWPPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50551644(CHEMBL4745937)copy SMILES
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human FLT3 D835Y mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KWPPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50551644(CHEMBL4745937)copy SMILES
Affinity DataKd:  115nMAssay Description:Binding affinity to human partial length FLT3 ITD/F691L double mutant expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KWPPubMed
LigandPNGBDBM50551644(CHEMBL4745937)copy SMILES
Affinity DataEC50:  2.49E+3nMAssay Description:Inhibition of human RET incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KWPPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50551644(CHEMBL4745937)copy SMILES
Affinity DataEC50:  1.77E+3nMAssay Description:Inhibition of human FLT3 incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KWPPubMed
TargetEphrin type-A receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM50551644(CHEMBL4745937)copy SMILES
Affinity DataEC50:  3.26E+3nMAssay Description:Inhibition of human EPHA7 incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KWPPubMed
LigandPNGBDBM50551644(CHEMBL4745937)copy SMILES
Affinity DataEC50:  3.26E+3nMAssay Description:Inhibition of human ZAK incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KWPPubMed
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50551644(CHEMBL4745937)copy SMILES
Affinity DataEC50:  2.49E+3nMAssay Description:Inhibition of human DDR2 incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KWPPubMed
TargetCyclin-dependent kinase 16(Homo sapiens (Human))TBA
LigandPNGBDBM50551644(CHEMBL4745937)copy SMILES
Affinity DataEC50:  1.77E+3nMAssay Description:Inhibition of human CDK16 incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KWPPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50551644(CHEMBL4745937)copy SMILES
Affinity DataEC50:  3.86E+3nMAssay Description:Inhibition of human NTRK1 incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KWPPubMed
LigandPNGBDBM50551644(CHEMBL4745937)copy SMILES
Affinity DataEC50:  3.86E+3nMAssay Description:Inhibition of human MAP4K4 incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KWPPubMed