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SMILES Cc1ccc(C)c(Nc2c(Cl)cnc3ccc(Br)cc23)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50552360   

TargetTumor necrosis factor(Homo sapiens (Human))TBA
LigandPNGBDBM50552360(CHEMBL4789269)copy SMILES
Affinity DataIC50: 840nMAssay Description:Inhibition of exogenous human TNFalpha in HEK-Blue-CD40L cells assessed as reduction in TNF-alpha-induced NFkappaB activation incubated for 18 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46WM7PubMed
TargetTumor necrosis factor(Homo sapiens (Human))TBA
LigandPNGBDBM50552360(CHEMBL4789269)copy SMILES
Affinity DataIC50: 36nMAssay Description:Displacement of fluorescent labeled probe from human recombinant His-tagged TNFalpha (77 to 233 residues) expressed in Escherichia coli preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46WM7PubMed