null

SMILES C[C@H](NC(=O)[C@H](CC(=O)NC(C)(C)C)NC(=O)C(=O)c1c[nH]c2ccccc12)C(=O)NCc1cccc2ccccc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50554388   

TargetProteasome subunit beta type-8(Homo sapiens (Human))TBA
LigandPNGBDBM50554388(CHEMBL4759896)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3WB6PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))TBA
LigandPNGBDBM50554388(CHEMBL4759896)copy SMILES
Affinity DataIC50: 293nMAssay Description:Inhibition of human 20S constitutive proteasome beta 5 chymotrypsin-like activity in human HeLa cells incubated for 2 hrs by proteasome-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3WB6PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))TBA
LigandPNGBDBM50554388(CHEMBL4759896)copy SMILES
Affinity DataIC50: 15nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activity in human KARPAS-1106P cells incubated for 2 hrs by proteasome-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3WB6PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))TBA
LigandPNGBDBM50554388(CHEMBL4759896)copy SMILES
Affinity DataIC50: 59nMAssay Description:Inhibition of human constitutive 20S proteasome beta 5 chymotrypsin-like activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3WB6PubMed