null
SMILES C[C@@H](C1CC1)N1Cc2cc(cc(C)c2C1=O)-c1cnc2[nH]cc(-c3ccncc3)c2c1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50561837
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))TBA
Affinity DataIC50: 220nMAssay Description:Inhibition of PI3Kgamma in human THP-1 cells assessed as reduction in Akt phosphorylation at S473 residue incubated for 60 mins measured after 120 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of CYP1A2 (unknown origin) using phenacetin as substrate measured after 5 to 20 mins in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin) using diclofenac as substrate measured after 5 to 20 mins in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))TBA
Affinity DataIC50: 3.40nMAssay Description:Inhibition of PI3K p120gamma (unknown origin) using phosphatidylinositol 4,5-bisphosphate as substrate in presence of ATP incubated for 60 mins by AD...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of CYP2C19 (unknown origin) using S-mephenytoin as substrate measured after 5 to 20 mins in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrate measured after 5 to 20 mins in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP2C9 (unknown origin) using diclofenac as substrate measured after 5 to 20 mins in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair