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SMILES Nc1n[nH]c2cc(ccc12)-c1ccc(=O)n(Cc2cccc(Cl)c2)c1

InChI Key

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50562615   

LigandPNGBDBM50562615(CHEMBL4764756)copy SMILES
Affinity DataKi:  5.5nMAssay Description:ATP-competitive inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system ...More data for this Ligand-Target Pair
LigandPNGBDBM50562615(CHEMBL4764756)copy SMILES
Affinity DataKi:  14nMAssay Description:ATP-competitive inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20005TFPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM50562615(CHEMBL4764756)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin) using BFC as substrate measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20005TFPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))TBA
LigandPNGBDBM50562615(CHEMBL4764756)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant CYP1A2 (unknown origin) using CEC as substrate measured after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20005TFPubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))TBA
LigandPNGBDBM50562615(CHEMBL4764756)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant CYP2B6 (unknown origin) using EFC as substrate measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20005TFPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))TBA
LigandPNGBDBM50562615(CHEMBL4764756)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) using CEC as substrate measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20005TFPubMed
LigandPNGBDBM50562615(CHEMBL4764756)copy SMILES
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair
LigandPNGBDBM50562615(CHEMBL4764756)copy SMILES
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20005TFPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM50562615(CHEMBL4764756)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant CYP2D6 (unknown origin) using AMMC as substrate measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20005TFPubMed