null

SMILES NS(=O)(=O)c1ccc(cc1)-c1cnc2[nH]nc(C(=O)c3c(F)ccc(NS(=O)(=O)Cc4ccccc4)c3F)c2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50567686   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))TBA
LigandPNGBDBM50567686(CHEMBL4798975)copy SMILES
Affinity DataKd:  450nMAssay Description:Binding affinity to wild-type human partial length BRAF (S429 to E741 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6X0KPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50567686(CHEMBL4798975)copy SMILES
Affinity DataKd:  210nMAssay Description:Binding affinity to wild-type human full length JNK1 (M1 to Q384 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6X0KPubMed
LigandPNGBDBM50567686(CHEMBL4798975)copy SMILES
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to wild-type human partial length MAP4K5 (M1 to P297 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6X0KPubMed
LigandPNGBDBM50567686(CHEMBL4798975)copy SMILES
Affinity DataIC50: 146nMAssay Description:Inhibition of MKK4 (unknown origin) by PanQinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6X0KPubMed
LigandPNGBDBM50567686(CHEMBL4798975)copy SMILES
Affinity DataKd:  5.00E+3nMAssay Description:Binding affinity to wild-type human full length MKK7 (M1 to R419 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6X0KPubMed
LigandPNGBDBM50567686(CHEMBL4798975)copy SMILES
Affinity DataKd:  5.00E+3nMAssay Description:Binding affinity to wild-type human partial length ZAK (M1 to L331 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6X0KPubMed
LigandPNGBDBM50567686(CHEMBL4798975)copy SMILES
Affinity DataKd:  1.70nMAssay Description:Binding affinity to wild-type human partial length MKK4 (S84 to D399 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6X0KPubMed