null

SMILES CC(NC(=O)c1[nH]cc(Cc2ccc(nc2)C(F)(F)F)c1C)c1cc(C)on1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50567964   

LigandPNGBDBM50567964(CHEMBL4858336 | US11903936, Compound 29)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21-DE3 using L-dihydroorotate as substrate by steady-state DCIP methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CD4PubMed
LigandPNGBDBM50567964(CHEMBL4858336 | US11903936, Compound 29)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21-DE3 using L-dihydroorotate as substrate by steady-state DCIP methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CD4PubMed
LigandPNGBDBM50567964(CHEMBL4858336 | US11903936, Compound 29)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21-DE3 using L-dihydroorotate as substrate by steady-state DCIP methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CD4PubMed
LigandPNGBDBM50567964(CHEMBL4858336 | US11903936, Compound 29)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21-DE3 using L-dihydroorotate as substrate by steady-state DCIP methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CD4PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))TBA
LigandPNGBDBM50567964(CHEMBL4858336 | US11903936, Compound 29)copy SMILES
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50567964(CHEMBL4858336 | US11903936, Compound 29)copy SMILES
Affinity DataEC50:  6.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50567964(CHEMBL4858336 | US11903936, Compound 29)copy SMILES
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50567964(CHEMBL4858336 | US11903936, Compound 29)copy SMILES
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50567964(CHEMBL4858336 | US11903936, Compound 29)copy SMILES
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50567964(CHEMBL4858336 | US11903936, Compound 29)copy SMILES
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))TBA
LigandPNGBDBM50567964(CHEMBL4858336 | US11903936, Compound 29)copy SMILES
Affinity DataEC50:  6.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. vivax)TBA
LigandPNGBDBM50567964(CHEMBL4858336 | US11903936, Compound 29)copy SMILES
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails