null

SMILES CCc1c(C)c2cc3[nH]c(cc4nc([C@@H](CCC(=O)Nc5ccc(cc5)C(=O)Nc5ccccc5N)[C@@H]4C)c(C(=O)OC)c4[nH]c(cc1n2)c(C)c4C(=O)OC)c(C)c3C=C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50569267   

TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50569267(CHEMBL4852895)copy SMILES
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human recombinant HDAC1 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate by measuring fluorescence intensity incubated for 30 mins by micropla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03CX3PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50569267(CHEMBL4852895)copy SMILES
Affinity DataIC50: 2.65E+3nMAssay Description:Inhibition of human recombinant HDAC2 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate by measuring fluorescence intensity incubated for 30 mins by micropla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03CX3PubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))TBA
LigandPNGBDBM50569267(CHEMBL4852895)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC10 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate by measuring fluorescence intensity incubated for 30 mins by micropl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03CX3PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50569267(CHEMBL4852895)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC6 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate by measuring fluorescence intensity incubated for 30 mins by micropla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03CX3PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50569267(CHEMBL4852895)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC8 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate by measuring fluorescence intensity incubated for 30 mins by micropla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03CX3PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))TBA
LigandPNGBDBM50569267(CHEMBL4852895)copy SMILES
Affinity DataIC50: 7.21E+4nMAssay Description:Inhibition of human recombinant HDAC3 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate by measuring fluorescence intensity incubated for 30 mins by micropla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03CX3PubMed