null

SMILES Cc1ccc2NC(=O)CN([C@H](c3cc(C)cc(C)c3)c2c1)C(=O)c1ccc(Br)s1

InChI Key

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50580051   

TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50580051(CHEMBL5070897)copy SMILES
Affinity DataIC50: 77nMAssay Description:Inhibition of N-terminal hexa-His-tagged/TEV cleavage site fused human full length PRMT6 expressed in baculovirus infected Sf9 insect cells using bio...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50580051(CHEMBL5070897)copy SMILES
Affinity DataIC50: 600nMAssay Description:Inhibition of FLAG-tagged PRMT6 (unknown origin) expressed in HEK293T assessed as reduction in H4R3me2a level measured after 20 hrs by SDS gel electr...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50580051(CHEMBL5070897)copy SMILES
Affinity DataIC50: 900nMAssay Description:Inhibition of FLAG-tagged PRMT6 (unknown origin) expressed in HEK293T assessed as reduction in H3R2me2a level measured after 20 hrs by SDS gel electr...More data for this Ligand-Target Pair