null

SMILES C[C@H]1NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O)C(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50581319   

TargetMelanocortin receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM50581319(BIM-22493 | RM-493 | SETMELANOTIDE | Setmelanotide)copy SMILES
Affinity DataKi:  4.10nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in HEK2936E cell membrane measured after 16-23 hrs by 1450 microbeta trilux scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N301TQPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM50581319(BIM-22493 | RM-493 | SETMELANOTIDE | Setmelanotide)copy SMILES
Affinity DataKi:  4.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C50R5PubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50581319(BIM-22493 | RM-493 | SETMELANOTIDE | Setmelanotide)copy SMILES
Affinity DataKi:  4.60nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK2936E cell membrane measured after 16-23 hrs by 1450 microbeta trilux scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N301TQPubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50581319(BIM-22493 | RM-493 | SETMELANOTIDE | Setmelanotide)copy SMILES
Affinity DataKi:  4.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C50R5PubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))TBA
LigandPNGBDBM50581319(BIM-22493 | RM-493 | SETMELANOTIDE | Setmelanotide)copy SMILES
Affinity DataKi:  13nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC3R expressed in HEK2936E cell membrane measured after 16-23 hrs by 1450 microbeta trilux scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N301TQPubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))TBA
LigandPNGBDBM50581319(BIM-22493 | RM-493 | SETMELANOTIDE | Setmelanotide)copy SMILES
Affinity DataKi:  13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C50R5PubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))TBA
LigandPNGBDBM50581319(BIM-22493 | RM-493 | SETMELANOTIDE | Setmelanotide)copy SMILES
Affinity DataEC50:  0.151nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C50R5PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM50581319(BIM-22493 | RM-493 | SETMELANOTIDE | Setmelanotide)copy SMILES
Affinity DataEC50:  0.398nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C50R5PubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50581319(BIM-22493 | RM-493 | SETMELANOTIDE | Setmelanotide)copy SMILES
Affinity DataEC50:  0.158nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C50R5PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM50581319(BIM-22493 | RM-493 | SETMELANOTIDE | Setmelanotide)copy SMILES
Affinity DataEC50: >0.0501nMAssay Description:Agonist activity at human melanocortin receptor 4 expressed in human T-REx-293 cells using high doxycycline assessed as stimulation of intracellular ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N301TQPubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))TBA
LigandPNGBDBM50581319(BIM-22493 | RM-493 | SETMELANOTIDE | Setmelanotide)copy SMILES
Affinity DataIC50: 1.91E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC5R expressed in HEK2936E cell membrane measured after 16-23 hrs by 1450 microbeta trilux scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N301TQPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM50581319(BIM-22493 | RM-493 | SETMELANOTIDE | Setmelanotide)copy SMILES
Affinity DataEC50:  0.389nMAssay Description:Agonist activity at human melanocortin receptor 4 expressed in human T-REx-293 cells using low doxycycline assessed as stimulation of intracellular c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N301TQPubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))TBA
LigandPNGBDBM50581319(BIM-22493 | RM-493 | SETMELANOTIDE | Setmelanotide)copy SMILES
Affinity DataIC50: 1.86E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C50R5PubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50581319(BIM-22493 | RM-493 | SETMELANOTIDE | Setmelanotide)copy SMILES
Affinity DataEC50:  0.158nMAssay Description:Agonist activity at human melanocortin receptor 1 expressed in human T-Rex-293 cells assessed as stimulation of intracellular cAMP accumulation incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N301TQPubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))TBA
LigandPNGBDBM50581319(BIM-22493 | RM-493 | SETMELANOTIDE | Setmelanotide)copy SMILES
Affinity DataEC50:  0.151nMAssay Description:Agonist activity at human melanocortin receptor 3 expressed in human T-REx-293 cells assessed as stimulation of intracellular cAMP accumulation incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N301TQPubMed