null

SMILES CC(=O)NC1CCN(CC1)c1ncnc2[nH]cc(-c3cccc(Cl)c3)c12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50583984   

TargetSerine/threonine-protein kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50583984(CHEMBL5089935)copy SMILES
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human STK4 (43 to 431 residues) expressed in Escherichia coli using myelin basic protein as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52TH8PubMed
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))TBA
LigandPNGBDBM50583984(CHEMBL5089935)copy SMILES
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human STK3 (18 to 311 residues) expressed in Escherichia coli using myelin basic protein as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52TH8PubMed
LigandPNGBDBM50583984(CHEMBL5089935)copy SMILES
Affinity DataIC50: 1.39E+3nMAssay Description:Displacement of K5 tracer from full length C-terminal NanoLuc fused human LRRK2 expressed in HEK293T cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52TH8PubMed
TargetSerine/threonine-protein kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50583984(CHEMBL5089935)copy SMILES
Affinity DataIC50: 122nMAssay Description:Displacement of K5 tracer from full length C-terminal NanoLuc fused human STK4 expressed in HEK293T cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52TH8PubMed
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))TBA
LigandPNGBDBM50583984(CHEMBL5089935)copy SMILES
Affinity DataIC50: 139nMAssay Description:Displacement of K5 tracer from full length C-terminal NanoLuc fused human STK3 expressed in HEK293T cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52TH8PubMed