BindingDB

null

SMILES O=C(Nc1cc(ccn1)C(=O)Nc1cnccc1-c1ccccc1)C1CC1

InChI Key

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 37 hits for monomerid = 50613392

Serine/threonine-protein kinase pim-1(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 5.00E+4nMMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Glycogen synthase kinase-3 beta(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 9.80nMMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

3D Structure (crystal)

Ribosomal protein S6 kinase alpha-1(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 5.00E+4nMMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Tyrosine-protein kinase SYK(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 5.00E+4nMMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 2.00E+3nMMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid PDB

Tyrosine-protein kinase JAK3(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 2.00E+3nMMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Rho-associated protein kinase 1(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 2.00E+3nMMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Rho-associated protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 2.00E+3nMMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid PDB

Tyrosine-protein kinase Srms(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 2.00E+3nMMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid PDB

High affinity nerve growth factor receptor(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 2.00E+3nMMore data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

BDNF/NT-3 growth factors receptor(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 2.00E+3nMMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 2.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Inhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 2.00E+3nMMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Tyrosine-protein kinase JAK1(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 2.00E+3nMMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Golgi-associated PDZ and coiled-coil motif-containing protein(Homo sapiens)TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 2.00E+3nMMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid PDB

Platelet-derived growth factor receptor beta(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 5.00E+4nMMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Mitogen-activated protein kinase 14(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 5.00E+4nMMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

MAP kinase-activated protein kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 5.00E+4nMMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Aurora kinase A(Mus musculus (mouse))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 5.00E+4nMMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid PDB

Insulin-like growth factor 1 receptor(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 5.00E+4nMMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Mast/stem cell growth factor receptor Kit(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 5.00E+4nMMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid PDB

Tyrosine-protein kinase ABL1(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 5.00E+4nMMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Platelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 5.00E+4nMMore data for this Ligand-Target Pair

MMDB KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

PC cid PC sid PDB

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 2.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Mitogen-activated protein kinase 8(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 2.00E+3nMMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Tyrosine-protein kinase Lck(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 2.00E+3nMMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid PDB

Tyrosine-protein kinase JAK2(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 2.00E+3nMMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Casein kinase II subunit alpha'(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 2.00E+3nMMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 2.00E+3nMMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Cyclin-dependent kinase 2(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 2.00E+3nMMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Aurora kinase B(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 2.00E+3nMMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid PDB

Tyrosine-protein kinase BTK(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 2.00E+3nMMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 8.00E+4nMMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Cytochrome P450 4B1(Homo sapiens)TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 2.00E+4nMMore data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid PDB

Glycogen synthase kinase-3 beta(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 320nMMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

3D Structure (crystal)

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 5.5nMMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid PDB

3D Structure (crystal)

Protein kinase C theta type(Homo sapiens (Human))TBA

PNG

BDBM50613392(CHEMBL5270581)copy SMILES

IC50: 5.00E+4nMMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Targets 35 ▿
- Non-receptor tyrosine-protein kinase TYK2 2
- Glycogen synthase kinase-3 beta 2
- Tyrosine-protein kinase Lck 1
- Tyrosine-protein kinase BTK 1
- Insulin-like growth factor 1 receptor 1
- High affinity nerve growth factor receptor 1
- Serine/threonine-protein kinase pim-1 1
- Tyrosine-protein kinase JAK1 1
- Potassium voltage-gated channel subfamily H member 2 1
- Mitogen-activated protein kinase 8 1
- Golgi-associated PDZ and coiled-coil motif-containing protein 1
- Tyrosine-protein kinase SYK 1
- Mast/stem cell growth factor receptor Kit 1
- Ribosomal protein S6 kinase alpha-1 1
- Mitogen-activated protein kinase 14 1
- Aurora kinase B 1
- Aurora kinase A 1
- Glycogen synthase kinase-3 alpha 1
- Tyrosine-protein kinase Srms 1
- Interleukin-1 receptor-associated kinase 4 1
- Inhibitor of nuclear factor kappa-B kinase subunit beta 1
- Platelet-derived growth factor receptor alpha/beta 1
- Tyrosine-protein kinase ABL1 1
- Macrophage colony-stimulating factor 1 receptor 1
- Protein kinase C theta type 1
- Cyclin-dependent kinase 2 1
- Tyrosine-protein kinase JAK3 1
- Cytochrome P450 4B1 1
- Tyrosine-protein kinase JAK2 1
- Rho-associated protein kinase 2 1
- MAP kinase-activated protein kinase 2 1
- Rho-associated protein kinase 1 1
- Platelet-derived growth factor receptor beta 1
- BDNF/NT-3 growth factors receptor 1
- Casein kinase II subunit alpha' 1
Publications 0 ▿
Institutions 0 ▿
Affinity: 5.5 to 8.0E+4 nM▿
- IC50 37
- Affinity ≤ nM
Xtal structures: 1
Docked structures: 0
Catalog Cmpds: 0