null

SMILES COC(=O)N1C[C@H](C)N([C@H](C)C1)c1ncc2[nH]nc(-c3ccc(nc3)N3CCN[C@H](C)C3)c2n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 518186   

TargetActivin receptor type-1 [147-509](Homo sapiens (Human))TBA
LigandPNGBDBM518186(US11111247, Example 17)copy SMILES
Affinity DataIC50: 100nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2571G50US Patent
TargetActivin receptor type-1 [147-509](Homo sapiens (Human))TBA
LigandPNGBDBM518186(US11111247, Example 17)copy SMILES
Affinity DataIC50: 100nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2571G50US Patent
TargetActivin receptor type-1 [147-509](Homo sapiens (Human))TBA
LigandPNGBDBM518186(US11111247, Example 17)copy SMILES
Affinity DataIC50: 100nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2571G50US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))TBA
LigandPNGBDBM518186(US11111247, Example 17)copy SMILES
Affinity DataIC50: 100nMAssay Description:un-Phosphorylated (UP): The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2571G50US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM518186(US11111247, Example 17)copy SMILES
Affinity DataIC50: 300nMAssay Description:un-Phosphorylated (UP): The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2571G50US Patent
TargetHepcidin(Homo sapiens)TBA
LigandPNGBDBM518186(US11111247, Example 17)copy SMILES
Affinity DataIC50: 7.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78K72PubMed
TargetActivin receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM518186(US11111247, Example 17)copy SMILES
Affinity DataIC50: 0.850nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78K72PubMed
TargetActivin receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM518186(US11111247, Example 17)copy SMILES
Affinity DataIC50: 27nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78K72PubMed
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))TBA
LigandPNGBDBM518186(US11111247, Example 17)copy SMILES
Affinity DataIC50: 5.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78K72PubMed
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))TBA
LigandPNGBDBM518186(US11111247, Example 17)copy SMILES
Affinity DataIC50: 251nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78K72PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM518186(US11111247, Example 17)copy SMILES
Affinity DataIC50: 26nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78K72PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM518186(US11111247, Example 17)copy SMILES
Affinity DataIC50: 100nMAssay Description:un-Phosphorylated (UP): The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2571G50US Patent