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SMILES Cc1ccc2[nH]nc(-c3ccc(cc3)C(N)=O)c2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 558866   

LigandPNGBDBM558866(US11370770, Compound 6r)copy SMILES
Affinity DataIC50: 560nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
LigandPNGBDBM558866(US11370770, Compound 6r)copy SMILES
Affinity DataIC50: 200nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
LigandPNGBDBM558866(US11370770, Compound 6r)copy SMILES
Affinity DataIC50: 510nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM558866(US11370770, Compound 6r)copy SMILES
Affinity DataIC50: 3.90E+3nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))TBA
LigandPNGBDBM558866(US11370770, Compound 6r)copy SMILES
Affinity DataIC50: 3.70E+3nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetMAP kinase-activated protein kinase 3(Homo sapiens (Human))TBA
LigandPNGBDBM558866(US11370770, Compound 6r)copy SMILES
Affinity DataIC50: 4.10E+3nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))TBA
LigandPNGBDBM558866(US11370770, Compound 6r)copy SMILES
Affinity DataIC50: 1.90E+4nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))TBA
LigandPNGBDBM558866(US11370770, Compound 6r)copy SMILES
Affinity DataIC50: 2.10E+3nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM558866(US11370770, Compound 6r)copy SMILES
Affinity DataIC50: 6.10E+3nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent