null

SMILES CN(C)Cc1ccc(NC(=O)c2cccc(c2)[C@@H]2C[C@H]2C(=O)Nc2ccc3cncc(Cl)c3c2)nc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 569294   

TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM569294(US11427563, Compound 36)copy SMILES
Affinity DataKi:  1nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5JVKUS Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM569294(US11427563, Compound 36)copy SMILES
Affinity DataKi:  6nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5JVKUS Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))TBA
LigandPNGBDBM569294(US11427563, Compound 36)copy SMILES
Affinity DataKi:  211nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5JVKUS Patent
LigandPNGBDBM569294(US11427563, Compound 36)copy SMILES
Affinity DataKi:  1.19E+3nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5JVKUS Patent