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SMILES COc1cc(OC)cc(c1)-c1cc2cnc(NCCCN3CCN(C)CC3)cc2nc1N

InChI Key InChIKey=NLUPPEQIXOCYEE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 6146   

TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
University of Auckland

LigandPNGBDBM6146(1,6-naphthyridine 15 | 3-(3,5-Dimethoxyphenyl)-N7-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6146(1,6-naphthyridine 15 | 3-(3,5-Dimethoxyphenyl)-N7-...)copy SMILEScopy InChI
Affinity DataIC50: 180nMpH: 7.8 T: 2°CAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6146(1,6-naphthyridine 15 | 3-(3,5-Dimethoxyphenyl)-N7-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6146(1,6-naphthyridine 15 | 3-(3,5-Dimethoxyphenyl)-N7-...)copy SMILEScopy InChI
Affinity DataIC50: 44nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed