null

SMILES Cn1ccc2cc(F)c3c4[nH]c5ccccc5c4c4C(=O)NC(=O)c4c3c12

InChI Key InChIKey=YNVJFXDCRAXAKP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 6812   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6812(23-fluoro-18-methyl-3,13,18-triazahexacyclo[14.7.0...)copy SMILEScopy InChI
Affinity DataIC50: 67nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Lilly Research Laboratories

LigandPNGBDBM6812(23-fluoro-18-methyl-3,13,18-triazahexacyclo[14.7.0...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6812(23-fluoro-18-methyl-3,13,18-triazahexacyclo[14.7.0...)copy SMILEScopy InChI
Affinity DataIC50: 86nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6812(23-fluoro-18-methyl-3,13,18-triazahexacyclo[14.7.0...)copy SMILEScopy InChI
Affinity DataIC50: 16nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed