null

SMILES Oc1ccc2-c3[nH]c4ccc(Br)cc4c3CC(=O)Nc2c1

InChI Key InChIKey=PMQCIJDDBNRBBC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 7322   

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
Universitat Hamburg

LigandPNGBDBM7322(14-bromo-5-hydroxy-8,18-diazatetracyclo[9.7.0.0^{2...)copy SMILEScopy InChI
Affinity DataIC50: 600nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050TRPubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
Universitat Hamburg

LigandPNGBDBM7322(14-bromo-5-hydroxy-8,18-diazatetracyclo[9.7.0.0^{2...)copy SMILEScopy InChI
Affinity DataIC50: 830nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050TRPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£t Braunschweig

Curated by ChEMBL
LigandPNGBDBM7322(14-bromo-5-hydroxy-8,18-diazatetracyclo[9.7.0.0^{2...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9C1VPubMed
LigandPNGBDBM7322(14-bromo-5-hydroxy-8,18-diazatetracyclo[9.7.0.0^{2...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9C1VPubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
Universitat Hamburg

LigandPNGBDBM7322(14-bromo-5-hydroxy-8,18-diazatetracyclo[9.7.0.0^{2...)copy SMILEScopy InChI
Affinity DataIC50: 18nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050TRPubMed