null

SMILES C1COc2ccc(Nc3nccc(n3)-c3cnn4ncccc34)cc2OC1

InChI Key InChIKey=CXHLTNFGZLWOKU-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 8138   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM8138(N-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-4-{pyraz...)copy SMILEScopy InChI
Affinity DataKi:  1nM IC50: 10nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49HJPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM8138(N-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-4-{pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 316nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49HJPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM8138(N-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-4-{pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.2 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49HJPubMed