null

SMILES Fc1ccc2\C(CCc2c1)=C/c1cccnc1

InChI Key InChIKey=WLUDJBASYYHRDC-WQLSENKSSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 8587   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8587((3-Pyridylmethylene)indane 5b | 3-{[(1Z)-5-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 125nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN075FPubMed
TargetAromatase(Homo sapiens (Human))
University of Calcutta

Curated by ChEMBL
LigandPNGBDBM8587((3-Pyridylmethylene)indane 5b | 3-{[(1Z)-5-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 2.49E+3nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53GHPubMed
TargetAromatase(Homo sapiens (Human))
University of Calcutta

Curated by ChEMBL
LigandPNGBDBM8587((3-Pyridylmethylene)indane 5b | 3-{[(1Z)-5-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 2.49E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN075FPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8587((3-Pyridylmethylene)indane 5b | 3-{[(1Z)-5-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN075FPubMed