null

SMILES COc1cc(ccc1NC(=O)CC(C)(C)c1ccccc1)-c1nn([C@H]2CC[C@@H](CC2)N2CCN(C)CC2)c2ncnc(N)c12

InChI Key InChIKey=CUIYKFICQYRIMQ-DIVCQZSQSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 8805   

TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8805(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 31nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8805(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 910nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8805(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 3.46E+4nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8805(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed