null

SMILES COc1cc2ccccc2cc1-n1ccnc1

InChI Key InChIKey=HDJQGQGNKJFUSV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 8917   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8917(1-(3-methoxynaphthalen-2-yl)-1H-imidazole | Imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 81nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8917(1-(3-methoxynaphthalen-2-yl)-1H-imidazole | Imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetAromatase(Homo sapiens (Human))
UNIVERSITAT DES SAARLANDES

US Patent
LigandPNGBDBM8917(1-(3-methoxynaphthalen-2-yl)-1H-imidazole | Imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 129nMpH: 7.4Assay Description:The enzyme was obtained from the microsome fraction of fresh human placenta (St. Josephs Krankenhaus, Saarbrucken-Dudweiler, Germany) according to th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2445KBNUS Patent
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8917(1-(3-methoxynaphthalen-2-yl)-1H-imidazole | Imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 5.02E+3nMT: 2°CAssay Description:V79 MZh11B1 and V79 MZh 11B2 cells (8˙10^5 cells per well) were grown to confluency on 24-well cell culture plates with 1.9 cm^2 culture area per...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2445KBNUS Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8917(1-(3-methoxynaphthalen-2-yl)-1H-imidazole | Imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 40nMT: 2°CAssay Description:V79 MZh11B1 and V79 MZh 11B2 cells (8˙10^5 cells per well) were grown to confluency on 24-well cell culture plates with 1.9 cm^2 culture area per...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2445KBNUS Patent
TargetAromatase(Homo sapiens (Human))
UNIVERSITAT DES SAARLANDES

US Patent
LigandPNGBDBM8917(1-(3-methoxynaphthalen-2-yl)-1H-imidazole | Imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 129nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed