Compile Data Set for Download or QSAR
Found 260 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3'
LigandPNGBDBM50395892(CHEMBL2163772)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MC1PubMed
LigandPNGBDBM50395887(CHEMBL2163770)copy SMILEScopy InChI
Affinity DataKi:  90nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MC1PubMed
LigandPNGBDBM50395894(CHEMBL2163771)copy SMILEScopy InChI
Affinity DataKi:  700nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MC1PubMed
LigandPNGBDBM50395888(CHEMBL2163769)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MC1PubMed
LigandPNGBDBM50395893(CHEMBL1165662)copy SMILEScopy InChI
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MC1PubMed
LigandPNGBDBM7453(1-aza-9-oxafluorene deriv. 7b | 4-methoxy-3-phenyl...)copy SMILEScopy InChI
Affinity DataKi:  5.30E+3nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MC1PubMed
LigandPNGBDBM50395890(CHEMBL2163774)copy SMILEScopy InChI
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MC1PubMed
LigandPNGBDBM50395891(CHEMBL2163773)copy SMILEScopy InChI
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MC1PubMed
LigandPNGBDBM50395889(CHEMBL2163768)copy SMILEScopy InChI
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MC1PubMed
LigandPNGBDBM50191929(2-(4-(4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
LigandPNGBDBM50191913(CHEMBL384350 | N-(2-methyl-4-(2-(pyrrolidin-1-yl)e...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
LigandPNGBDBM50191918(CHEMBL212552 | N-(2-methyl-4-(2-(piperidin-1-yl)et...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
LigandPNGBDBM50191924(CHEMBL377449 | N-(2-methyl-4-(2-morpholinoethyl)ph...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
LigandPNGBDBM50191922(CHEMBL212299 | trans-N1-(4-(1H-pyrrolo[2,3-b]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin) after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9SXVPubMed
LigandPNGBDBM50191925(4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-N-o-tolylpyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
LigandPNGBDBM50338873(CHEMBL1684800 | N-(5-Amino-1-(4-methoxybenzyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CD3PubMed
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3GBSPubMed
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of Cyclin B-cyclin-dependent kinase 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B01SBPubMed
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of CDK1/cyclinBMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0HG5PubMed
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of cyclin dependent kinase 1-cyclinBMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B01SBPubMed
LigandPNGBDBM50191914(CHEMBL212833 | N-(2-chlorophenyl)-4-(1H-pyrrolo[2,...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against Cyclin D1-cyclin-dependent kinase 4 by measuring the phosphorylation of RbINGMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z89BTCPubMed
LigandPNGBDBM50191919(CHEMBL380301 | N-(2-bromophenyl)-4-(1H-pyrrolo[2,3...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
LigandPNGBDBM50191912(CHEMBL385478 | N-cyclohexyl-4-(1H-pyrrolo[2,3-b]py...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
LigandPNGBDBM50132003((Z)-1H,1''H-[2,3'']Biindolylidene-3,2''-dione 3-ox...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of CDK1/cyclinBMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0HG5PubMed
LigandPNGBDBM50366800(OLOMOUCINE II)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8MK1PubMed
LigandPNGBDBM50169892(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833RK0PubMed
LigandPNGBDBM7238((3Z)-3-(1H-imidazol-5-ylmethylidene)-5-methoxy-2,3...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of CDK1/cyclinBMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0HG5PubMed
LigandPNGBDBM7491((4Z)-4-(2-amino-5-oxo-3,5-dihydro-4H-imidazol-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of CDK1/cyclinBMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0HG5PubMed
LigandPNGBDBM7263(9-cyanopaullone | 9-oxo-8,18-diazatetracyclo[9.7.0...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of CDK1/cyclin B expressed in M phase starfish oocyteMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9C1VPubMed
LigandPNGBDBM50191928(1-(3-(2-(cyclohexylamino)pyrimidin-4-yl)-1H-pyrrol...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
LigandPNGBDBM7262(14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of CDK1/cyclin B expressed in M phase starfish oocyteMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9C1VPubMed
LigandPNGBDBM7262(14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of CDK1/cyclinBMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0HG5PubMed
LigandPNGBDBM50191916(4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-N-p-tolylpyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
LigandPNGBDBM7265(4,5-dimethoxy-9-oxo-8,18-diazatetracyclo[9.7.0.0^{...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of CDK1/cyclin B expressed in M phase starfish oocyteMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9C1VPubMed
LigandPNGBDBM50191923(CHEMBL213023 | N-(2-methoxyphenyl)-4-(1H-pyrrolo[2...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
LigandPNGBDBM50191932(CHEMBL377048 | N-(2-fluorophenyl)-4-(1H-pyrrolo[2,...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
LigandPNGBDBM7269(3-(6-oxo-9-trifluoromethyl-5,6,7,12-tetrahydro-ind...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of Cyclin-dependent kinase 1-cyclin B from Starfish oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z60N98PubMed
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8MK1PubMed
LigandPNGBDBM50191917(CHEMBL378768 | N-phenyl-4-(1H-pyrrolo[2,3-b]pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
LigandPNGBDBM50191926(4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-N-(2-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of human recombinant CDK1/Cyclin B by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67H7NPubMed
LigandPNGBDBM50191920(4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-N-m-tolylpyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
LigandPNGBDBM50191915(CHEMBL213277 | N-(2-ethylphenyl)-4-(1H-pyrrolo[2,3...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
LigandPNGBDBM10642(2-[({2-[(1-hydroxy-3-methylbutan-2-yl)amino]-9-(pr...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8MK1PubMed
LigandPNGBDBM50120508(2-(3-hydroxypropylamino)-6-(o -hydroxybenzylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8MK1PubMed
LigandPNGBDBM10635(3-[({2-[(1-hydroxy-3-methylbutan-2-yl)amino]-9-(pr...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8MK1PubMed
LigandPNGBDBM50191921(CHEMBL215048 | N-cyclohexyl-4-(1-(methylsulfonyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 128nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
LigandPNGBDBM50191931(2-(4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 139nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
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