Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 144 [31-434]'
TargetCytochrome P450 144 [31-434](Mycobacterium tuberculosis)
University of Cambridge

LigandPNGBDBM222346(CYP144A1 ligand, 1)copy SMILEScopy InChI
Affinity DataKd:  8.20E+4nMpH: 7.0Assay Description:Optical titrations to determine the binding affinity (KD values) of ligands were carried out on a Cary 60 UV−visible spectrophotometer (Varian,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1JF3PubMed
TargetCytochrome P450 144 [31-434](Mycobacterium tuberculosis)
University of Cambridge

LigandPNGBDBM222347(CYP144A1 ligand, 2)copy SMILEScopy InChI
Affinity DataKd:  2.00E+5nMpH: 7.0Assay Description:Optical titrations to determine the binding affinity (KD values) of ligands were carried out on a Cary 60 UV−visible spectrophotometer (Varian,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1JF3PubMed
TargetCytochrome P450 144 [31-434](Mycobacterium tuberculosis)
University of Cambridge

LigandPNGBDBM222349(CYP144A1 ligand, 4)copy SMILEScopy InChI
Affinity DataKd:  2.30E+5nMpH: 7.0Assay Description:Optical titrations to determine the binding affinity (KD values) of ligands were carried out on a Cary 60 UV−visible spectrophotometer (Varian,...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1JF3PubMed
TargetCytochrome P450 144 [31-434](Mycobacterium tuberculosis)
University of Cambridge

LigandPNGBDBM24656(4-PIM | 4-Phenylimidazole | 4-phenyl-1H-imidazole ...)copy SMILEScopy InChI
Affinity DataKd:  2.98E+6nMpH: 7.0Assay Description:Optical titrations to determine the binding affinity (KD values) of ligands were carried out on a Cary 60 UV−visible spectrophotometer (Varian,...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1JF3PubMed
TargetCytochrome P450 144 [31-434](Mycobacterium tuberculosis)
University of Cambridge

LigandPNGBDBM7886(1-PIM | 1-phenyl-1H-imidazole | 1-phenylimidazole ...)copy SMILEScopy InChI
Affinity DataKd:  2.90E+5nMpH: 7.0Assay Description:Optical titrations to determine the binding affinity (KD values) of ligands were carried out on a Cary 60 UV−visible spectrophotometer (Varian,...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1JF3PubMed
TargetCytochrome P450 144 [31-434](Mycobacterium tuberculosis)
University of Cambridge

LigandPNGBDBM222348(CYP144A1 ligand, 3)copy SMILEScopy InChI
Affinity DataKd:  1.40E+5nMpH: 7.5 T: 2°CAssay Description:ITC binding isotherms were recorded on a MicroCal ITC200 instrument (MalvernInstruments). Titrations were conducted at 25 °C by injecting aliquots (2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1JF3PubMed