Compile Data Set for Download or QSAR
Found 22 Enz. Inhib. hit(s) with Target = 'Dihydroorotase'
TargetDihydroorotase(Escherichia coli)
Texas A&M University

LigandPNGBDBM85254(4,6-dioxo-piperidine-2-carboxylic acid, 3)copy SMILEScopy InChI
Affinity DataKi:  7.60E+7nMpH: 7.0Assay Description:The DHO-catalyzed hydrolysis of dihydrooroate was monitored spectrophotoetrically at 230 and 280 nm using a SPECTRAmax (Molecular Device) plate reade...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X065MDPubMed
TargetDihydroorotase(Escherichia coli)
Texas A&M University

LigandPNGBDBM85254(4,6-dioxo-piperidine-2-carboxylic acid, 3)copy SMILEScopy InChI
Affinity DataKi:  2.10E+8nMpH: 8.0Assay Description:The DHO-catalyzed hydrolysis of dihydrooroate was monitored spectrophotoetrically at 230 and 280 nm using a SPECTRAmax (Molecular Device) plate reade...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X065MDPubMed
TargetDihydroorotase(Escherichia coli)
Texas A&M University

LigandPNGBDBM85254(4,6-dioxo-piperidine-2-carboxylic acid, 3)copy SMILEScopy InChI
Affinity DataKi:  4.40E+8nMpH: 9.0Assay Description:The DHO-catalyzed hydrolysis of dihydrooroate was monitored spectrophotoetrically at 230 and 280 nm using a SPECTRAmax (Molecular Device) plate reade...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X065MDPubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University of Illinois at Chicago

LigandPNGBDBM154573(8-(trifluoromethyl)-9H-purin-6-amine (4) | acs.jme...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.5Assay Description:The fluorogenic substrate used in this study was ubiquitin-AMC (Boston Biochem). All assays were performed in 384-well black plates (Corning) in a to...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086426PubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University of Illinois at Chicago

LigandPNGBDBM50007789(CHEMBL1173044 | GRL-0667 | N-(2H-1,3-benzodioxol-5...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.5Assay Description:The fluorogenic substrate used in this study was ubiquitin-AMC (Boston Biochem). All assays were performed in 384-well black plates (Corning) in a to...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086426PubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University of Illinois at Chicago

LigandPNGBDBM50536772(CHEMBL1604422)copy SMILEScopy InChI
Affinity DataKd:  1.70E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells in presence of N-carbamyl-L-aspart...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q6BPubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University of Illinois at Chicago

LigandPNGBDBM50536771(CHEMBL1518262)copy SMILEScopy InChI
Affinity DataKd:  2.81E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells in presence of N-carbamyl-L-aspart...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q6BPubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University of Illinois at Chicago

LigandPNGBDBM50536774(CHEMBL4560356)copy SMILEScopy InChI
Affinity DataKd: >1.00E+6nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells in presence of N-carbamyl-L-aspart...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q6BPubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University of Illinois at Chicago

LigandPNGBDBM50495373(CHEMBL3110262)copy SMILEScopy InChI
Affinity DataKd:  2.15E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells in presence of N-carbamyl-L-aspart...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q6BPubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University of Illinois at Chicago

LigandPNGBDBM50536775(CHEMBL4572519)copy SMILEScopy InChI
Affinity DataKd:  3.80E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells by surface plasmon resonance analy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q6BPubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University of Illinois at Chicago

LigandPNGBDBM50536775(CHEMBL4572519)copy SMILEScopy InChI
Affinity DataKd:  3.14E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells in presence of N-carbamyl-L-aspart...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q6BPubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University of Illinois at Chicago

LigandPNGBDBM50536774(CHEMBL4560356)copy SMILEScopy InChI
Affinity DataKd:  6.70E+4nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells by surface plasmon resonance analy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q6BPubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University of Illinois at Chicago

LigandPNGBDBM50136492(6-Methoxy-2,3,4,9-tetrahydro-1H-beta-carboline | 6...)copy SMILEScopy InChI
Affinity DataKd:  6.75E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells in presence of N-carbamyl-L-aspart...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q6BPubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University of Illinois at Chicago

LigandPNGBDBM50136492(6-Methoxy-2,3,4,9-tetrahydro-1H-beta-carboline | 6...)copy SMILEScopy InChI
Affinity DataKd:  5.88E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells by surface plasmon resonance analy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q6BPubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University of Illinois at Chicago

LigandPNGBDBM50536776(CHEMBL4580574)copy SMILEScopy InChI
Affinity DataKd:  6.70E+4nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells by surface plasmon resonance analy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q6BPubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University of Illinois at Chicago

LigandPNGBDBM50536769(CHEMBL4574809)copy SMILEScopy InChI
Affinity DataKd:  2.10E+4nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells by surface plasmon resonance analy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q6BPubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University of Illinois at Chicago

LigandPNGBDBM50536773(CHEMBL4532317)copy SMILEScopy InChI
Affinity DataKd:  6.70E+4nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells by surface plasmon resonance analy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q6BPubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University of Illinois at Chicago

LigandPNGBDBM50536772(CHEMBL1604422)copy SMILEScopy InChI
Affinity DataKd:  1.70E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells by surface plasmon resonance analy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q6BPubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University of Illinois at Chicago

LigandPNGBDBM50536771(CHEMBL1518262)copy SMILEScopy InChI
Affinity DataKd:  1.57E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells by surface plasmon resonance analy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q6BPubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University of Illinois at Chicago

LigandPNGBDBM50536770(CHEMBL4580389)copy SMILEScopy InChI
Affinity DataKd:  6.70E+4nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells by surface plasmon resonance analy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q6BPubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University of Illinois at Chicago

LigandPNGBDBM50536769(CHEMBL4574809)copy SMILEScopy InChI
Affinity DataKd:  1.44E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells in presence of N-carbamyl-L-aspart...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q6BPubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University of Illinois at Chicago

LigandPNGBDBM50495373(CHEMBL3110262)copy SMILEScopy InChI
Affinity DataKd:  2.05E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells by surface plasmon resonance analy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q6BPubMed