BindingDB PrimarySearch

Found 5 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [696-1210,T790M]'

Epidermal growth factor receptor [696-1210,T790M](Homo sapiens (Human))
Chemical Genomics Centre of the Max Planck Society

BDBM4567(4-anilinoquinazoline deriv. 2 | BMC163482 Compound...)copy SMILEScopy InChI

IC50: 1.20nMpH: 7.5 T: 2°CAssay Description:The kinase reaction for EGFR consisted of BSA-supplemented kinase buffer, kinase, peptide, and ATP. For IC50 determinations, 10 different concentrati...More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2R20ZQ4PubMed PDB

3D Structure (crystal)

Epidermal growth factor receptor [696-1210,T790M](Homo sapiens (Human))
Chemical Genomics Centre of the Max Planck Society

BDBM4583((2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4...)copy SMILEScopy InChI

IC50: 3nMpH: 7.5 T: 2°CAssay Description:The kinase reaction for EGFR consisted of BSA-supplemented kinase buffer, kinase, peptide, and ATP. For IC50 determinations, 10 different concentrati...More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2R20ZQ4PubMed

Epidermal growth factor receptor [696-1210,T790M](Homo sapiens (Human))
Chemical Genomics Centre of the Max Planck Society

BDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)copy SMILEScopy InChI

IC50: 260nMpH: 7.5 T: 2°CAssay Description:The kinase reaction for EGFR consisted of BSA-supplemented kinase buffer, kinase, peptide, and ATP. For IC50 determinations, 10 different concentrati...More data for this Ligand-Target Pair

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Details Article
BindingDB Entry DOI: 10.7270/Q2R20ZQ4PubMed MMDB
PDB

3D Structure (crystal)

Epidermal growth factor receptor [696-1210,T790M](Homo sapiens (Human))
Chemical Genomics Centre of the Max Planck Society

BDBM31826(4-aminoquinazoline, 2a | BMC163482 Compound 3 | CH...)copy SMILEScopy InChI

IC50: 360nMpH: 7.5 T: 2°CAssay Description:The kinase reaction for EGFR consisted of BSA-supplemented kinase buffer, kinase, peptide, and ATP. For IC50 determinations, 10 different concentrati...More data for this Ligand-Target Pair

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Details Article
BindingDB Entry DOI: 10.7270/Q2R20ZQ4PubMed PDB

3D Structure (crystal)

Epidermal growth factor receptor [696-1210,T790M](Homo sapiens (Human))
Chemical Genomics Centre of the Max Planck Society

BDBM102620(BMX-IN-1 | N-[5-[9-[4-(methanesulfonamido)phenyl]-...)copy SMILEScopy InChI

IC50: 4.28E+3nMMore data for this Ligand-Target Pair

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Details Article
BindingDB Entry DOI: 10.7270/Q2V40SVGPubMed