Compile Data Set for Download or QSAR
Found 27 Enz. Inhib. hit(s) with Target = 'Isoleucyl-tRNA synthetase'
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217841(REVEROMYCIN A)copy SMILEScopy InChI
Affinity DataIC50: 1.97nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MX8PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50093001((4aR,6S,7R,7aS)-7-[2-((S)-2-Amino-3-methyl-butyryl...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PN94W3PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50093003((4aR,6S,7R,7aS)-7-[2-((2S,3S)-2-Amino-3-methyl-pen...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PN94W3PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50093004((4aR,6S,7R,7aS)-7-[2-((2S,3S)-2-Amino-3-methyl-pen...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PN94W3PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50093002((4aR,6S,7R,7aS)-7-[2-((2S,3S)-2-Amino-3-methyl-pen...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PN94W3PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217935(CHEMBL114859)copy SMILEScopy InChI
Affinity DataIC50: 44.4nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MX8PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50093005((4aR,6S,7R,7aS)-7-[2-((S)-2-Amino-4-methyl-pentano...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PN94W3PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217844(CHEMBL115953)copy SMILEScopy InChI
Affinity DataIC50: 74.4nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MX8PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217934(CHEMBL321686)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MX8PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217938(CHEMBL112182)copy SMILEScopy InChI
Affinity DataIC50: 195nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MX8PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217849(CHEMBL115317)copy SMILEScopy InChI
Affinity DataIC50: 244nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MX8PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217839(CHEMBL327131)copy SMILEScopy InChI
Affinity DataIC50: 353nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MX8PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50093006((4aR,6S,7R,7aS)-6-((2S,3S)-2-Benzyloxycarbonylamin...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PN94W3PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217846(CHEMBL332420)copy SMILEScopy InChI
Affinity DataIC50: 742nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MX8PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217933(CHEMBL115057)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MX8PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217840(CHEMBL324768)copy SMILEScopy InChI
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MX8PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217937(CHEMBL114949)copy SMILEScopy InChI
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MX8PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217932(CHEMBL115260)copy SMILEScopy InChI
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MX8PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217845(CHEMBL324327)copy SMILEScopy InChI
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MX8PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217843(CHEMBL115081)copy SMILEScopy InChI
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MX8PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217936(CHEMBL115949)copy SMILEScopy InChI
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MX8PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217842(REVEROMYCIN B)copy SMILEScopy InChI
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MX8PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217848(CHEMBL326691)copy SMILEScopy InChI
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MX8PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217838(CHEMBL115939)copy SMILEScopy InChI
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MX8PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217847(CHEMBL114741)copy SMILEScopy InChI
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MX8PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50093007((4aR,6S,7R,7aS)-4-Carbamoyl-2-methyl-6-((S)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 6.10E+3nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PN94W3PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50093008((4aR,6S,7R,7aS)-4-Carbamoyl-6-hydroxy-2-methyl-7-[...)copy SMILEScopy InChI
Affinity DataIC50: 2.23E+4nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PN94W3PubMed