Compile Data Set for Download or QSAR
Found 296 Enz. Inhib. hit(s) with Target = 'Prostaglandin E synthase 2'
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168766(3-(1-(4-chlorobenzyl)-5-(2-fluoro-2'-methylbipheny...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q1XPubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168776(3-(5-(2'-chloro-2-fluorobiphenyl-4-yl)-1-(4-chloro...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q1XPubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168760(3-(1-(4-chlorobenzyl)-5-(2-fluoro-2'-methoxybiphen...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q1XPubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168785(3-(5-(2'-acetyl-2-fluorobiphenyl-4-yl)-1-(4-chloro...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q1XPubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168761(3-(1-(4-chlorobenzyl)-5-(2-fluorobiphenyl-4-yl)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q1XPubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168770(3-(1-(4-chlorobenzyl)-5-(2,2'-difluorobiphenyl-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q1XPubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168782(3-(1-(4-chlorobenzyl)-5-(3-fluoro-4-(pyridin-3-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q1XPubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168768(3-(5-(biphenyl-4-yl)-1-(4-chlorobenzyl)-3-methyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q1XPubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168787(3-(1-(4-chlorobenzyl)-5-(2-chlorobiphenyl-4-yl)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q1XPubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181966(US9145380, 169)copy SMILEScopy InChI
Affinity DataIC50: 22nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168788(3-(1-(4-chlorobenzyl)-5-(2-fluoro-4'-methylbipheny...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q1XPubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182037(US9145380, 240)copy SMILEScopy InChI
Affinity DataIC50: 31nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168777(3-[1-(4-Chloro-benzyl)-5-(3-fluoro-4-pyrazin-2-yl-...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q1XPubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168763(3-(1-(4-chlorobenzyl)-5-(2-fluoro-3'-methylbipheny...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q1XPubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181846(US9145380, 49)copy SMILEScopy InChI
Affinity DataIC50: 36nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181802(US9145380, 5)copy SMILEScopy InChI
Affinity DataIC50: 40nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182009(US9145380, 212)copy SMILEScopy InChI
Affinity DataIC50: 41nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181815(US9145380, 18)copy SMILEScopy InChI
Affinity DataIC50: 44nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182005(US9145380, 208)copy SMILEScopy InChI
Affinity DataIC50: 55nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181833(US9145380, 36)copy SMILEScopy InChI
Affinity DataIC50: 57nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181903(US9145380, 106)copy SMILEScopy InChI
Affinity DataIC50: 74nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181803(US9145380, 6)copy SMILEScopy InChI
Affinity DataIC50: 74nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182008(US9145380, 211)copy SMILEScopy InChI
Affinity DataIC50: 75nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181822(US9145380, 25)copy SMILEScopy InChI
Affinity DataIC50: 77nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181801(US9145380, 4)copy SMILEScopy InChI
Affinity DataIC50: 79nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181980(US9145380, 183)copy SMILEScopy InChI
Affinity DataIC50: 81nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181849(US9145380, 52)copy SMILEScopy InChI
Affinity DataIC50: 84nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181889(US9145380, 92)copy SMILEScopy InChI
Affinity DataIC50: 91nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182004(US9145380, 207)copy SMILEScopy InChI
Affinity DataIC50: 97nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182021(US9145380, 224)copy SMILEScopy InChI
Affinity DataIC50: 100nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182014(US9145380, 217)copy SMILEScopy InChI
Affinity DataIC50: 110nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181840(US9145380, 43)copy SMILEScopy InChI
Affinity DataIC50: 110nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181831(US9145380, 34)copy SMILEScopy InChI
Affinity DataIC50: 120nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181798(US9145380, 1)copy SMILEScopy InChI
Affinity DataIC50: 130nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182013(US9145380, 216)copy SMILEScopy InChI
Affinity DataIC50: 130nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181847(US9145380, 50)copy SMILEScopy InChI
Affinity DataIC50: 130nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182025(US9145380, 228)copy SMILEScopy InChI
Affinity DataIC50: 130nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182028(US9145380, 231)copy SMILEScopy InChI
Affinity DataIC50: 130nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181904(US9145380, 107)copy SMILEScopy InChI
Affinity DataIC50: 140nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181800(US9145380, 3)copy SMILEScopy InChI
Affinity DataIC50: 140nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182030(US9145380, 233)copy SMILEScopy InChI
Affinity DataIC50: 150nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181834(US9145380, 37)copy SMILEScopy InChI
Affinity DataIC50: 160nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168762(3-[5-Biphenyl-3-yl-1-(4-chloro-benzyl)-3-methyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q1XPubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181850(US9145380, 53)copy SMILEScopy InChI
Affinity DataIC50: 160nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181832(US9145380, 35)copy SMILEScopy InChI
Affinity DataIC50: 170nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM182015(US9145380, 218)copy SMILEScopy InChI
Affinity DataIC50: 180nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181813(US9145380, 16)copy SMILEScopy InChI
Affinity DataIC50: 190nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181881(US9145380, 84)copy SMILEScopy InChI
Affinity DataIC50: 190nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181961(US9145380, 164)copy SMILEScopy InChI
Affinity DataIC50: 190nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM181918(US9145380, 121)copy SMILEScopy InChI
Affinity DataIC50: 220nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9PXMUS Patent
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