Compile Data Set for Download or QSAR
Found 17 Enz. Inhib. hit(s) with Target = 'Tubulin polymerization-promoting protein'
TargetTubulin polymerization-promoting protein(Homo sapiens (Human))
University of Virginia

LigandPNGBDBM59225(Boronic acid, cis-6 | Boronic acid, trans-6)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:IC50 values for inhibition of cell growth using MCF-7 cell line were obtained by measuring the amount of total cell protein with the sulforhodamine B...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN43HCPubMed
TargetTubulin polymerization-promoting protein(Homo sapiens (Human))
University of Virginia

LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:IC50 values for inhibition of cell growth using MCF-7 cell line were obtained by measuring the amount of total cell protein with the sulforhodamine B...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN43HCPubMed
TargetTubulin polymerization-promoting protein(Homo sapiens (Human))
University of Virginia

LigandPNGBDBM59225(Boronic acid, cis-6 | Boronic acid, trans-6)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:IC50 values for inhibition of cell growth using MCF-7 cell line were obtained by measuring the amount of total cell protein with the sulforhodamine B...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN43HCPubMed
TargetTubulin polymerization-promoting protein(Homo sapiens (Human))
University of Virginia

LigandPNGBDBM59225(Boronic acid, cis-6 | Boronic acid, trans-6)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Tubulin polymerization was followed turbidimetrically at 350nm in Beckman model DU-7400 and DU-7500 spectrophotometers equipped with electric tempera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN43HCPubMed
TargetTubulin polymerization-promoting protein(Homo sapiens (Human))
University of Virginia

LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Tubulin polymerization was followed turbidimetrically at 350nm in Beckman model DU-7400 and DU-7500 spectrophotometers equipped with electric tempera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN43HCPubMed
TargetTubulin polymerization-promoting protein(Homo sapiens (Human))
University of Virginia

LigandPNGBDBM59225(Boronic acid, cis-6 | Boronic acid, trans-6)copy SMILEScopy InChI
Affinity DataIC50: 7.80E+3nMAssay Description:Tubulin polymerization was followed turbidimetrically at 350nm in Beckman model DU-7400 and DU-7500 spectrophotometers equipped with electric tempera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN43HCPubMed
TargetTubulin polymerization-promoting protein(Bos taurus)
Rohm and Haas Company

Curated by ChEMBL
LigandPNGBDBM50099939(2',3',4'-Trimethoxy-biphenyl-2-carbonitrile | CHEM...)copy SMILEScopy InChI
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of Bos taurus (bovine) brain tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8C18PubMed
TargetTubulin polymerization-promoting protein(Bos taurus)
Rohm and Haas Company

Curated by ChEMBL
LigandPNGBDBM50099940(2,3,4,4'-Tetramethoxy-2'-nitro-biphenyl | CHEMBL31...)copy SMILEScopy InChI
Affinity DataEC50:  6.25E+3nMAssay Description:Inhibition of Bos taurus (bovine) brain tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8C18PubMed
TargetTubulin polymerization-promoting protein(Bos taurus)
Rohm and Haas Company

Curated by ChEMBL
LigandPNGBDBM50099941(4,2',3',4'-Tetramethoxy-biphenyl-2-carbonitrile | ...)copy SMILEScopy InChI
Affinity DataEC50:  6.25E+3nMAssay Description:Inhibition of Bos taurus (bovine) brain tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8C18PubMed
TargetTubulin polymerization-promoting protein(Bos taurus)
Rohm and Haas Company

Curated by ChEMBL
LigandPNGBDBM50099943(2,3,4,4'-Tetramethoxy-2'-methyl-biphenyl | CHEMBL3...)copy SMILEScopy InChI
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of Bos taurus (bovine) brain tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8C18PubMed
TargetTubulin polymerization-promoting protein(Bos taurus)
Rohm and Haas Company

Curated by ChEMBL
LigandPNGBDBM50099948(2,3,4-Trimethoxy-2'-nitro-biphenyl | CHEMBL32021)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of Bos taurus (bovine) brain tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8C18PubMed
TargetTubulin polymerization-promoting protein(Bos taurus)
Rohm and Haas Company

Curated by ChEMBL
LigandPNGBDBM50099942(6-(2,3,4-Trimethoxy-phenyl)-cyclohex-3-enecarbonit...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of Bos taurus (bovine) brain tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8C18PubMed
TargetTubulin polymerization-promoting protein(Bos taurus)
Rohm and Haas Company

Curated by ChEMBL
LigandPNGBDBM50099946(1,2,3-Trimethoxy-4-(6-nitro-cyclohex-3-enyl)-benze...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of Bos taurus (bovine) brain tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8C18PubMed
TargetTubulin polymerization-promoting protein(Bos taurus)
Rohm and Haas Company

Curated by ChEMBL
LigandPNGBDBM50099947(2,3,4,4'-Tetramethoxy-biphenyl | CHEMBL28250)copy SMILEScopy InChI
Affinity DataEC50:  6.25E+3nMAssay Description:Inhibition of Bos taurus (bovine) brain tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8C18PubMed
TargetTubulin polymerization-promoting protein(Bos taurus)
Rohm and Haas Company

Curated by ChEMBL
LigandPNGBDBM50099938(((1S,6R)-6-Nitro-cyclohex-3-enyl)-benzene | CHEMBL...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of Bos taurus (bovine) brain tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8C18PubMed
TargetTubulin polymerization-promoting protein(Bos taurus)
Rohm and Haas Company

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)copy SMILEScopy InChI
Affinity DataEC50:  750nMAssay Description:Inhibition of Bos taurus (bovine) brain tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8C18PubMed
TargetTubulin polymerization-promoting protein(Bos taurus)
Rohm and Haas Company

Curated by ChEMBL
LigandPNGBDBM50099944(1-Methoxy-3-((1S,6R)-6-nitro-cyclohex-3-enyl)-benz...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of Bos taurus (bovine) brain tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8C18PubMed