Compile Data Set for Download or QSAR
Found 121 with Last Name = 'brault' and Initial = 'a'
LigandPNGBDBM50406141(CHEMBL5286547)copy SMILEScopy InChI
Affinity DataKi:  1.80E+3nMAssay Description:Antagonistic activity against M2 muscarinic receptor in guinea pig left atrium derived by plotting log(DR - 1) vs log[antagonist]More data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50406139(CHEMBL5281816)copy SMILEScopy InChI
Affinity DataKi:  3.60E+3nMAssay Description:Antagonistic activity against M2 muscarinic receptor in guinea pig left atrium derived by plotting log(DR - 1) vs log[antagonist]More data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50406140(CHEMBL5284779)copy SMILEScopy InChI
Affinity DataKi:  4.00E+3nMAssay Description:Antagonistic activity against M2 muscarinic receptor in guinea pig left atrium derived by plotting log(DR - 1) vs log[antagonist]More data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50406144(CHEMBL5283506)copy SMILEScopy InChI
Affinity DataKi:  1.10E+4nMAssay Description:Antagonistic activity against M2 muscarinic receptor in guinea pig left atrium derived by plotting log(DR - 1) vs log[antagonist]More data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50406145(CHEMBL5287800)copy SMILEScopy InChI
Affinity DataKi:  1.70E+4nMAssay Description:Antagonistic activity against M2 muscarinic receptor in guinea pig left atrium derived by plotting log(DR - 1) vs log[antagonist]More data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50406143(CHEMBL5287916)copy SMILEScopy InChI
Affinity DataKi:  1.90E+4nMAssay Description:Antagonistic activity against M2 muscarinic receptor in guinea pig left atrium derived by plotting log(DR - 1) vs log[antagonist]More data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50406142(CHEMBL5280788)copy SMILEScopy InChI
Affinity DataKi:  3.70E+4nMAssay Description:Antagonistic activity against M2 muscarinic receptor in guinea pig left atrium derived by plotting log(DR - 1) vs log[antagonist]More data for this Ligand-Target Pair
In DepthDetails
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146201(6-Phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)copy SMILEScopy InChI
Affinity DataIC50: 0.75nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERalpha expressed in 293T cellsMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50175419(4-(2-phenyl-1H-indol-3-yl)phenol | CHEMBL371012)copy SMILEScopy InChI
Affinity DataIC50: 1.12nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbeta expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879CKPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)copy SMILEScopy InChI
Affinity DataIC50: 1.18nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbeta expressed in 293T cellsMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146201(6-Phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM19459(5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbeta expressed in 293T cellsMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50175413(4-(4-phenyl-5-(trifluoromethyl)isoxazol-3-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbeta expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879CKPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146206(2-Benzyl-1-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-1...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146200((E)-3-[4-(6-Hydroxy-1-phenyl-3,4-dihydro-1H-isoqui...)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146223(2-Benzenesulfonyl-1-[4-(2-pyrrolidin-1-yl-ethoxy)-...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146216(2-(Naphthalene-1-sulfonyl)-1-[4-(2-pyrrolidin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146200((E)-3-[4-(6-Hydroxy-1-phenyl-3,4-dihydro-1H-isoqui...)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146222(1-Benzyl-2-phenyl-1,2,3,4-tetrahydro-isoquinolin-6...)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146199((E)-3-[4-(6-Hydroxy-1-phenyl-3,4-dihydro-1H-isoqui...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50175413(4-(4-phenyl-5-(trifluoromethyl)isoxazol-3-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 8.5nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERalpha expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879CKPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146199((E)-3-[4-(6-Hydroxy-1-phenyl-3,4-dihydro-1H-isoqui...)copy SMILEScopy InChI
Affinity DataIC50: 8.70nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146220(2,2,2-Trifluoro-1-[(R)-6-hydroxy-1-(4-hydroxy-phen...)copy SMILEScopy InChI
Affinity DataIC50: 8.90nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146205(2-Benzo[1,3]dioxol-5-ylmethyl-1-[4-(2-pyrrolidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 9.20nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146211(2,2,2-Trifluoro-1-[7-hydroxy-4-(4-hydroxy-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146207(4-(4-Hydroxy-phenyl)-2-(naphthalene-1-sulfonyl)-1,...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50175412(4-(3-(4-hydroxyphenyl)-1H-indol-2-yl)phenol | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 11.9nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbeta expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879CKPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM20585(2-phenyl-1-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-1...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146198(2-Benzyl-4-(4-hydroxy-phenyl)-1,2,3,4-tetrahydro-i...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50175417(4-(2-(3-methylisoxazol-4-yl)-1H-benzo[d]imidazol-1...)copy SMILEScopy InChI
Affinity DataIC50: 14.3nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbeta expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879CKPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50175415(4-(5-phenyl-2-(trifluoromethyl)-1H-imidazol-4-yl)p...)copy SMILEScopy InChI
Affinity DataIC50: 15.1nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbeta expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879CKPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146223(2-Benzenesulfonyl-1-[4-(2-pyrrolidin-1-yl-ethoxy)-...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146198(2-Benzyl-4-(4-hydroxy-phenyl)-1,2,3,4-tetrahydro-i...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146216(2-(Naphthalene-1-sulfonyl)-1-[4-(2-pyrrolidin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146204(1-[1-(4-Bromo-phenyl)-6-hydroxy-3,4-dihydro-1H-iso...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM20585(2-phenyl-1-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-1...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50175419(4-(2-phenyl-1H-indol-3-yl)phenol | CHEMBL371012)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERalpha expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879CKPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146208(1-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-2-(toluene...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146221(2-Phenyl-1-thiophen-2-yl-1,2,3,4-tetrahydro-isoqui...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146215(2,2,2-Trifluoro-1-(6-hydroxy-1-phenyl-3,4-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146213(CHEMBL93207 | [7-Hydroxy-4-(4-hydroxy-phenyl)-3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146207(4-(4-Hydroxy-phenyl)-2-(naphthalene-1-sulfonyl)-1,...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50175410(4-(2-(1-methyl-1H-pyrrol-2-yl)-1H-benzo[d]imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 28.1nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbeta expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879CKPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146202(2,2,2-Trifluoro-1-{6-hydroxy-1-[4-(2-pyrrolidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146226(2-(4-Propyl-benzenesulfonyl)-1-[4-(2-pyrrolidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM19459(5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 29.4nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERalpha expressed in 293T cellsMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146209(1-Cyclohexyl-2-phenyl-1,2,3,4-tetrahydro-isoquinol...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146224(1,2-Diphenyl-1,2,3,4-tetrahydro-isoquinolin-6-ol |...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50146206(2-Benzyl-1-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-1...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GBKPubMed
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