Compile Data Set for Download or QSAR
Found 184 with Last Name = 'calvet' and Initial = 'a'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Institut de Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Binding affinity against high affinity rolipram binding site (HARBS) was determined by displacing radioactive [3H]rolipram from brain membrane suspen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4Z9JPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Institut de Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of [3H]rolipram binding to Wistar rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50473085(CHEMBL146218)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Institut de Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Inhibition of [3H]rolipram binding to Wistar rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50473089(CHEMBL145390)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50473071(CHEMBL145499)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50473079(CHEMBL145258)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50473077(CHEMBL144258)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50473070(CHEMBL422653)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50473081(CHEMBL144404)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50473092(CHEMBL144245)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50473090(CHEMBL144287)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50473083(CHEMBL342285 | CI-1044)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50217563(CHEMBL125671)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50473080(CHEMBL423931)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Institut de Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50473080(CHEMBL423931)copy SMILEScopy InChI
Affinity DataIC50: 309nMAssay Description:Inhibition of [3H]rolipram binding to Wistar rat brain membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50217563(CHEMBL125671)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4Z9JPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Institut de Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50473075(CHEMBL343243)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of [3H]rolipram binding to Wistar rat brain membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50217559(CHEMBL123266)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4Z9JPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50473084(CHEMBL434516)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50223647(CHEMBL112366)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50217545(CHEMBL341304)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4Z9JPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50217561(CHEMBL340860)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4Z9JPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Institut de Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50223647(CHEMBL112366)copy SMILEScopy InChI
Affinity DataIC50: 654nMAssay Description:Inhibition of [3H]rolipram binding to Wistar rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50473082(CHEMBL144570)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50473075(CHEMBL343243)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50473072(CHEMBL357197)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50217546(CHEMBL125123)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50217546(CHEMBL125123)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4Z9JPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50217553(CHEMBL339749)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4Z9JPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50217551(CHEMBL419791)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4Z9JPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 930nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50217558(CHEMBL338684)copy SMILEScopy InChI
Affinity DataIC50: 960nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4Z9JPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50473087(CHEMBL341671)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Institut de Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50473082(CHEMBL144570)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]rolipram binding to Wistar rat brain membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Institut de Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217546(CHEMBL125123)copy SMILEScopy InChI
Affinity DataIC50: 1.09E+3nMAssay Description:Binding affinity against high affinity rolipram binding site (HARBS) was determined by displacing radioactive [3H]rolipram from brain membrane suspen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4Z9JPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50217550(CHEMBL111925 | CI-1018)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50217550(CHEMBL111925 | CI-1018)copy SMILEScopy InChI
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4Z9JPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50217557(CHEMBL123782)copy SMILEScopy InChI
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4Z9JPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50217555(CHEMBL332854)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4Z9JPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50217553(CHEMBL339749)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50473078(CHEMBL341662)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50217560(CHEMBL126581)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50217560(CHEMBL126581)copy SMILEScopy InChI
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4Z9JPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Institut de Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50473083(CHEMBL342285 | CI-1044)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of [3H]rolipram binding to Wistar rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50473088(CHEMBL434838)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50217549(CHEMBL332853)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4Z9JPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Institut de Recherche Jouveinal-Parke Davis

Curated by ChEMBL
LigandPNGBDBM50217545(CHEMBL341304)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Binding affinity against high affinity rolipram binding site (HARBS) was determined by displacing radioactive [3H]rolipram from brain membrane suspen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4Z9JPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50217552(CHEMBL339408)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68FSPubMed
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