Compile Data Set for Download or QSAR
Found 193 with Last Name = 'dömling' and Initial = 'a'
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50436050(CHEMBL1234332)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Binding affinity to MDM2 (unknown origin) expressed in Escherichia coli BL21(DE3) after 30 mins by fluorescence polarization assay in presence of P4 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50436049(CHEMBL2396744)copy SMILEScopy InChI
Affinity DataKi:  80nMAssay Description:Binding affinity to MDM2 (unknown origin) expressed in Escherichia coli BL21(DE3) after 30 mins by fluorescence polarization assay in presence of P4 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NWDPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50436048(CHEMBL2396745)copy SMILEScopy InChI
Affinity DataKi:  250nMAssay Description:Binding affinity to MDM2 (unknown origin) expressed in Escherichia coli BL21(DE3) after 30 mins by fluorescence polarization assay in presence of P4 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM17347((3R,6S,9aR)-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-...)copy SMILEScopy InChI
Affinity DataKi:  270nMAssay Description:Inhibition of XIAP by FP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FQ9PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50436047(CHEMBL1233798)copy SMILEScopy InChI
Affinity DataKi:  920nMAssay Description:Binding affinity to MDM2 (unknown origin) expressed in Escherichia coli BL21(DE3) after 30 mins by fluorescence polarization assay in presence of P4 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50299823((6R,7S)-6,7-bis(4-bromophenyl)-7,11-dihydro-6H-chr...)copy SMILEScopy InChI
Affinity DataKi:  1.23E+3nMAssay Description:Binding affinity to MDM2 (unknown origin) expressed in Escherichia coli BL21(DE3) after 30 mins by fluorescence polarization assay in presence of P4 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NWDPubMedMMDB
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50436041(CHEMBL2396747)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Antagonist activity at MDM2 (unknown origin)-p53 complex assessed as release of p53 by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NWDPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50436041(CHEMBL2396747)copy SMILEScopy InChI
Affinity DataKi:  5.00E+3nMAssay Description:Binding affinity to MDM2 (unknown origin) expressed in Escherichia coli BL21(DE3) by HSQC NMR spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NWDPubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50251652(Biphenyl-4-carboxylic acid {[4-(adamantan-1-ylamin...)copy SMILEScopy InChI
Affinity DataKi:  9.43E+3nMAssay Description:Inhibition of 5-carboxyfluorescein-labeled Flu-Bak-BH3 peptide binding to Bcl-w by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ083NPubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50251651(Biphenyl-4-carboxylic acid methyl-[(3-nitro-4-pipe...)copy SMILEScopy InChI
Affinity DataKi:  1.08E+4nMAssay Description:Inhibition of 5-carboxyfluorescein-labeled Flu-Bak-BH3 peptide binding to Bcl-w by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ083NPubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50251616(CHEMBL521427 | biphenyl-4-carboxylic acid methyl-[...)copy SMILEScopy InChI
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of 5-carboxyfluorescein-labeled Flu-Bak-BH3 peptide binding to Bcl-w by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ083NPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50436041(CHEMBL2396747)copy SMILEScopy InChI
Affinity DataKi:  1.60E+4nMAssay Description:Binding affinity to MDM2 (unknown origin) expressed in Escherichia coli BL21(DE3) after 30 mins by fluorescence polarization assay in presence of P4 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NWDPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50436046(CHEMBL2396750)copy SMILEScopy InChI
Affinity DataKi:  3.30E+4nMAssay Description:Binding affinity to MDM2 (unknown origin) expressed in Escherichia coli BL21(DE3) after 30 mins by fluorescence polarization assay in presence of P4 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NWDPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50436045(CHEMBL2396755)copy SMILEScopy InChI
Affinity DataKi:  3.50E+4nMAssay Description:Binding affinity to MDM2 (unknown origin) expressed in Escherichia coli BL21(DE3) after 30 mins by fluorescence polarization assay in presence of P4 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NWDPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50436044(CHEMBL2396748)copy SMILEScopy InChI
Affinity DataKi:  4.30E+4nMAssay Description:Binding affinity to MDM2 (unknown origin) expressed in Escherichia coli BL21(DE3) after 30 mins by fluorescence polarization assay in presence of P4 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NWDPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50436043(CHEMBL2396756)copy SMILEScopy InChI
Affinity DataKi:  5.40E+4nMAssay Description:Binding affinity to MDM2 (unknown origin) expressed in Escherichia coli BL21(DE3) after 30 mins by fluorescence polarization assay in presence of P4 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NWDPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50436041(CHEMBL2396747)copy SMILEScopy InChI
Affinity DataKi: >6.00E+4nMAssay Description:Antagonist activity at MDM2 (unknown origin)-p53 complex assessed as release of p53 by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NWDPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50436042(CHEMBL2396746)copy SMILEScopy InChI
Affinity DataKi:  6.00E+4nMAssay Description:Binding affinity to MDM2 (unknown origin) expressed in Escherichia coli BL21(DE3) after 30 mins by fluorescence polarization assay in presence of P4 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NWDPubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM642313((+)-(R)-(5-amino-5-(1-(2-((2- fluorobenzyl)amino)-...)copy SMILES
Affinity DataIC50: 2.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642313((+)-(R)-(5-amino-5-(1-(2-((2- fluorobenzyl)amino)-...)copy SMILES
Affinity DataIC50: 3.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-2, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM642315((+)-(R)-(5-amino-5-(1-(2-oxo-2- (phenethylamino)et...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-2, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM642314((-)-(S)-(5-amino-5-(1-(2-((2- fluorobenzyl)amino)-...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642287((5-amino-5-(1-(2-(((6-chloropyridin-3- yl)methyl)a...)copy SMILES
Affinity DataIC50: 5.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-2, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM642312((-)-(S)-(5-amino-5-(1-(2-((4- chlorobenzyl)amino)-...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-2, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM642218((5-amino-5-(1-(2-((4-chlorobenzyl) amino)-2-oxoeth...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642280((6-amino-6-(1-(2-((4- chlorobenzyl)amino)-2-oxoeth...)copy SMILES
Affinity DataIC50: 7.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-2, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM642208((5-amino-5-(1-(2-((2-fluorobenzyl)amino)- 2-oxoeth...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642270((5-amino-5-(1-(2-((2,4- difluorobenzyl)amino)-2-ox...)copy SMILES
Affinity DataIC50: 9.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642208((5-amino-5-(1-(2-((2-fluorobenzyl)amino)- 2-oxoeth...)copy SMILES
Affinity DataIC50: 9.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-2, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM642316((-)-(S)-(5-amino-5-(1-(2-oxo-2- (phenethylamino)et...)copy SMILES
Affinity DataIC50: 10.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642315((+)-(R)-(5-amino-5-(1-(2-oxo-2- (phenethylamino)et...)copy SMILES
Affinity DataIC50: 10.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642288((5-amino-5-(1-(2-((3-fluorobenzyl)amino)- 2-oxoeth...)copy SMILES
Affinity DataIC50: 10.6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642289((5-amino-5-(1-(2-((2,3- difluorobenzyl)amino)-2-ox...)copy SMILES
Affinity DataIC50: 11.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-2, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM642227((5-amino-5-(1-(2-oxo-2-(prop-2-yn-1- ylamino)ethyl...)copy SMILES
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642312((-)-(S)-(5-amino-5-(1-(2-((4- chlorobenzyl)amino)-...)copy SMILES
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642274((5-amino-5-(1-(2-((2,6- difluorobenzyl)amino)-2-ox...)copy SMILES
Affinity DataIC50: 12.4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642286((5-amino-5-(1-(2-oxo-2-((2,4,6- trifluorobenzyl)am...)copy SMILES
Affinity DataIC50: 12.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642290((5-amino-5-(1-(2-((2,5- difluorobenzyl)amino)-2-ox...)copy SMILES
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642219((5-amino-5-(1-(2-oxo-2-(((S)-1- phenylethyl)amino)...)copy SMILES
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-2, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM642221((5-Amino-5-(1-(2-oxo-2- (phenethylamino)ethyl)-1H-...)copy SMILES
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642281((6-amino-6-(1-(2-((2,4- dichlorobenzyl)amino)-2-ox...)copy SMILES
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642285((5-amino-5-(1-(2-oxo-2-((2,3,4,5- tetrafluorobenzy...)copy SMILES
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642316((-)-(S)-(5-amino-5-(1-(2-oxo-2- (phenethylamino)et...)copy SMILES
Affinity DataIC50: 13.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642218((5-amino-5-(1-(2-((4-chlorobenzyl) amino)-2-oxoeth...)copy SMILES
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642226((5-amino-5-(1-(2-(butylamino)-2- oxoethyl)-1H-tetr...)copy SMILES
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642297((5-amino-5-(1-(2-oxo-2-((2,4,5- trifluorobenzyl)am...)copy SMILES
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642221((5-Amino-5-(1-(2-oxo-2- (phenethylamino)ethyl)-1H-...)copy SMILES
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642299((5-amino-5-(1-(2-oxo-2-(((R)-1- phenylethyl)amino)...)copy SMILES
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642309((+)-(R)-(5-amino-5-(1-(2-oxo-2-(prop-2- yn-1-ylami...)copy SMILES
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM642273((5-amino-5-(1-(2-((4-chloro-2- fluorobenzyl)amino)...)copy SMILES
Affinity DataIC50: 15.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
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