Compile Data Set for Download or QSAR
Found 119 with Last Name = 'erdmann' and Initial = 'a'
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273478(CHEMBL4130224)copy SMILEScopy InChI
Affinity DataKi:  7.40E+4nMAssay Description:Mixed type inhibition of KDM5A (L88 to G353 residues) ARID/PHD1/2/3 deletion mutant (unknown origin) demethylation activity using H3(1-21)K4me3 pepti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
CNRS-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
CNRS-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075103(CHEBI:48202 | Nanafrocin)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of His6-tagged human recombinant DNMT3b expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-bio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6M36PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
CNRS-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin gallate | (-)-Epigallocatechi...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6M36PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
CNRS-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM24774(2,3-dichloro-1,4-dihydronaphthalene-1,4-dione | 2,...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6M36PubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM223320(KDOAM-25)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of KDM5A (M1 to L801 residues) PHD2/3 deletion mutant (unknown origin) demethylation activity preincubated for 10 mins followed by peptide...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM223320(KDOAM-25)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of KDM5A (M1 to L801 residues) PHD2/3 deletion mutant (unknown origin) demethylation activity preincubated for 10 mins followed by peptide...More data for this Ligand-Target Pair
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273472(CHEMBL4126235)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7B (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetLysine-specific demethylase 7A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273472(CHEMBL4126235)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetLysine-specific demethylase PHF2(Homo sapiens)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273472(CHEMBL4126235)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7C (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Homo sapiens (Human))
CNRS-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50448484(CHEMBL3126646)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of His6-tagged human recombinant DNMT3a expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-bio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6M36PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
CNRS-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075193(CHEMBL3414630)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6M36PubMed
TargetLysine-specific demethylase 7A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273469(CHEMBL4126406)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetLysine-specific demethylase 7A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273469(CHEMBL4126406)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
CNRS-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50430056(CHEMBL2336409 | SGI-1027)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6M36PubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
CNRS-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50430056(CHEMBL2336409 | SGI-1027)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of His6-tagged human recombinant DNMT3b expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-bio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6M36PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Homo sapiens (Human))
CNRS-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50430056(CHEMBL2336409 | SGI-1027)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of His6-tagged human recombinant DNMT3a expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-bio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6M36PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
CNRS-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50448484(CHEMBL3126646)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6M36PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
CNRS-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075182(CHEMBL3414633)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6M36PubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50270477(CHEMBL4127210)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from recombinant His6-tagged human KDM5A (PHD3) (1542 to 1660 residues) ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
CNRS-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075185(CHEMBL3414632)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6M36PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
CNRS-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075192(CHEMBL3414631)copy SMILES
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6M36PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
CNRS-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50495479(CHEMBL3109084)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant DNMT1 expressed in H19 cells assessed as inhibition of tritiated methyl incorporation from [3H]-labeled AdoMet into h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69Q3PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
CNRS-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM19459(5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6M36PubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM92787(WAG-003)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of H3K4me3 binding to Halo-tagged GST-fused KDM5A PHD3 domain (unknown origin) expressed in Escherichia coli by HaloTag-based peptide di...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273478(CHEMBL4130224)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from recombinant His6-tagged human KDM5A (PHD3) (1542 to 1660 residues) ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Homo sapiens (Human))
CNRS-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075182(CHEMBL3414633)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of His6-tagged human recombinant DNMT3a expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-bio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6M36PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
CNRS-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50495477(CHEMBL3109085)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant DNMT1 expressed in H19 cells assessed as inhibition of tritiated methyl incorporation from [3H]-labeled AdoMet into h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69Q3PubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM92788(WAG-005)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+4nMAssay Description:Displacement of H3K4me3 binding to Halo-tagged GST-fused KDM5A PHD3 domain (unknown origin) expressed in Escherichia coli by HaloTag-based peptide di...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetLysine-specific demethylase 7A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM92788(WAG-005)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetLysine-specific demethylase 7A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM92788(WAG-005)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Homo sapiens (Human))
CNRS-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075185(CHEMBL3414632)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of His6-tagged human recombinant DNMT3a expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-bio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6M36PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
CNRS-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50495478(CHEMBL3109076)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant DNMT1 expressed in H19 cells assessed as inhibition of tritiated methyl incorporation from [3H]-labeled AdoMet into h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69Q3PubMed
TargetLysine-specific demethylase 7A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273477(CHEMBL4129830)copy SMILEScopy InChI
Affinity DataIC50: 6.80E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
CNRS-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50495476(CHEMBL3109078)copy SMILEScopy InChI
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of human recombinant DNMT1 expressed in H19 cells assessed as inhibition of tritiated methyl incorporation from [3H]-labeled AdoMet into h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69Q3PubMed
TargetLysine-specific demethylase 7A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273474(CHEMBL4129980)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
CNRS-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50495480(CHEMBL3109079)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human recombinant DNMT1 expressed in H19 cells assessed as inhibition of tritiated methyl incorporation from [3H]-labeled AdoMet into h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69Q3PubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273478(CHEMBL4130224)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of KDM5A (M1 to L801 residues) PHD2/3 deletion mutant (unknown origin) demethylation activity preincubated for 10 mins followed by peptide...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM92788(WAG-005)copy SMILEScopy InChI
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of KDM5A (M1 to L801 residues) PHD2/3 deletion mutant (unknown origin) demethylation activity preincubated for 10 mins followed by peptide...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM92788(WAG-005)copy SMILEScopy InChI
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of KDM5A (M1 to L801 residues) PHD2/3 deletion mutant (unknown origin) demethylation activity preincubated for 10 mins followed by peptide...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetLysine-specific demethylase PHF2(Homo sapiens)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM18957((2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-di...)copy SMILEScopy InChI
Affinity DataIC50: 8.40E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7C (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetLysine-specific demethylase 7A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273478(CHEMBL4130224)copy SMILEScopy InChI
Affinity DataIC50: 8.60E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetLysine-specific demethylase 7A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273478(CHEMBL4130224)copy SMILEScopy InChI
Affinity DataIC50: 8.60E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetLysine-specific demethylase 7A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273476(CHEMBL4128152)copy SMILEScopy InChI
Affinity DataIC50: 9.80E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
CNRS-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50495481(CHEMBL3109077)copy SMILEScopy InChI
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant DNMT1 expressed in H19 cells assessed as inhibition of tritiated methyl incorporation from [3H]-labeled AdoMet into h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69Q3PubMed
TargetLysine-specific demethylase 7A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273476(CHEMBL4128152)copy SMILEScopy InChI
Affinity DataIC50: 9.80E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM18957((2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-di...)copy SMILEScopy InChI
Affinity DataIC50: 9.90E+4nMAssay Description:Inhibition of KDM5A (M1 to L801 residues) PHD2/3 deletion mutant (unknown origin) demethylation activity preincubated for 10 mins followed by peptide...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetLysine-specific demethylase 7A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50270479(CHEMBL4127094)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetLysine-specific demethylase 7A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273473(CHEMBL4127792)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273478(CHEMBL4130224)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7B (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01912PubMed
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