Compile Data Set for Download or QSAR
Found 560 with Last Name = 'estella' and Initial = 'a'
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)copy SMILEScopy InChI
Affinity DataIC50: 0.110nMAssay Description:Inhibition of recombinant full length C-terminal FLAG His-tagged human HDAC1 expressed in baculovirus infected Sf21 insect cells using RHK-K(Ac)-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9V8VPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)copy SMILEScopy InChI
Affinity DataIC50: 0.110nMAssay Description:Inhibition of full length recombinant human HDAC1 expressed in baculovirus infected Sf9 cells using RHKK-Ac as substrate by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP8448PubMed
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50196772(CHEMBL3936651)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMAssay Description:Inhibition of recombinant N-terminal GST tagged PDE6C (unknown origin) expressed in baculovirus infected Sf9 cells using cGMP as substrate by malachi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP8448PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)copy SMILEScopy InChI
Affinity DataIC50: 0.330nMAssay Description:Inhibition of recombinant full length C-terminal GST fusion-tagged human HDAC2 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9V8VPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)copy SMILEScopy InChI
Affinity DataIC50: 0.330nMAssay Description:Inhibition of full length recombinant human HDAC2 expressed in baculovirus infected Sf9 cells using RHKK-Ac as substrate by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP8448PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50196760(CHEMBL3954968)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE5A1 expressed in baculovirus infected Sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP8448PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50196765(CHEMBL3986487)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE5A1 expressed in baculovirus infected Sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP8448PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50088373(CHEBI:46295 | Vardenafil | cid_110634)copy SMILEScopy InChI
Affinity DataIC50: 0.890nMAssay Description:Inhibition of PDE5A (unknown origin)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50088373(CHEBI:46295 | Vardenafil | cid_110634)copy SMILEScopy InChI
Affinity DataIC50: 0.890nMAssay Description:Inhibition of recombinant human PDE5AMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50196643(CHEMBL3925737)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE5A1 expressed in baculovirus infected Sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP8448PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458485(CHEMBL4216635)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134MGPubMed
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458479(CHEMBL4212186)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PDE6C (unknown origin) using FAM-cGMP as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134MGPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458502(CHEMBL4203481)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134MGPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50196775(CHEMBL3926754)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE5A1 expressed in baculovirus infected Sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP8448PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50196636(CHEMBL3899814)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE5A1 expressed in baculovirus infected Sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP8448PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50575637(CHEMBL4845706)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of full length human C-terminal His-tagged/C-terminal Flag-tagged HDAC1 using fluorogenic acetylated peptide as substrate incubated for 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9V8VPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458500(CHEMBL4209220)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134MGPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))TBA
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9V8VPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))TBA
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP8448PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP8448PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9V8VPubMed
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50196675(CHEMBL3900593)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant N-terminal GST tagged PDE6C (unknown origin) expressed in baculovirus infected Sf9 cells using cGMP as substrate by malachi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP8448PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50196781(CHEMBL3898716)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE5A1 expressed in baculovirus infected Sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP8448PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458487(CHEMBL4214135)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134MGPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458496(CHEMBL4214699)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134MGPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50196669(CHEMBL3970984)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE5A1 expressed in baculovirus infected Sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP8448PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50575639(CHEMBL4858828)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of full length human C-terminal His-tagged/C-terminal Flag-tagged HDAC1 using fluorogenic acetylated peptide as substrate incubated for 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9V8VPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458490(CHEMBL4217166)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134MGPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50575638(CHEMBL4847870)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of full length human C-terminal His-tagged/C-terminal Flag-tagged HDAC1 using fluorogenic acetylated peptide as substrate incubated for 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9V8VPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50575609(CHEMBL4852593)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of full length human C-terminal His-tagged/C-terminal Flag-tagged HDAC1 using fluorogenic acetylated peptide as substrate incubated for 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9V8VPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50575636(CHEMBL4848955)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of full length human C-terminal His-tagged/C-terminal Flag-tagged HDAC1 using fluorogenic acetylated peptide as substrate incubated for 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9V8VPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of full length human N-terminal GST-tagged HDAC6 using fluorogenic acetylated peptide as substrate incubated for 30 mins by fluorescence p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9V8VPubMedDrugBank
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM22449(CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134MGPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE5A1 expressed in baculovirus infected Sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50196763(CHEMBL3956031)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE5A1 expressed in baculovirus infected Sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP8448PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50196642(CHEMBL3984639)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE5A1 expressed in baculovirus infected Sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP8448PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))TBA
LigandPNGBDBM50575621(CHEMBL4865830)copy SMILES
Affinity DataIC50: 4nMAssay Description:Inhibition of human G9a enzyme using histone monomethyl-H3K9 peptide as substrate incubated for 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9V8VPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50439674(RICOLINOSTAT | US10858323, Compound 2 | US11207431...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134MGPubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:Inhibition of full length recombinant human HDAC3/NCOR2 expressed in baculovirus infected Sf9 cells using RHKK-Ac as substrate by fluorescence analys...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP8448PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:Inhibition of C-terminal His-tagged recombinant human HDAC3 (1 to 428 residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residues) c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9V8VPubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50575609(CHEMBL4852593)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of full length human C-terminal His-tagged HDAC3/human N-terminal GST-agged NCOR2 using fluorogenic acetylated peptide as substrate incuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9V8VPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458482(CHEMBL4208487)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of PDE5A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134MGPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50196774(CHEMBL3895860)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE5A1 expressed in baculovirus infected Sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP8448PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50196637(CHEMBL3907730)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE5A1 expressed in baculovirus infected Sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP8448PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50196761(CHEMBL3966438)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE5A1 expressed in baculovirus infected Sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP8448PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50575640(CHEMBL4850570)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of full length human C-terminal His-tagged/C-terminal Flag-tagged HDAC1 using fluorogenic acetylated peptide as substrate incubated for 30...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9V8VPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of full length human recombinant C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells using fluorogenic HDAC subst...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50575623(CHEMBL4876993)copy SMILES
Affinity DataIC50: 6nMAssay Description:Inhibition of full length human C-terminal His-tagged/C-terminal Flag-tagged HDAC1 using fluorogenic acetylated peptide as substrate incubated for 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9V8VPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50196729(CHEMBL3923840)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE5A1 expressed in baculovirus infected Sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP8448PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50575621(CHEMBL4865830)copy SMILES
Affinity DataIC50: 7nMAssay Description:Inhibition of full length human C-terminal His-tagged/C-terminal Flag-tagged HDAC1 using fluorogenic acetylated peptide as substrate incubated for 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9V8VPubMed
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