Compile Data Set for Download or QSAR
Found 341 with Last Name = 'favia' and Initial = 'a'
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)copy SMILEScopy InChI
Affinity DataIC50: 0.0100nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Universita` degli Studi di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human CYP11B2 expressed in Chinese hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone/11-deoxycorticosteroneMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153438(CHEMBL3774873 | US9630914, Example 14)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153445(CHEMBL3775280 | US9630914, Example 15)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153438(CHEMBL3774873 | US9630914, Example 14)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Universit£ di Bari

Curated by ChEMBL
LigandPNGBDBM50422881(CHEMBL213955)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondria MAOB by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4K1NPubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153379(CHEMBL3775979 | US9630914, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Universit£ di Bari

Curated by ChEMBL
LigandPNGBDBM50422876(CHEMBL212661)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondria MAOB by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4K1NPubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)copy SMILEScopy InChI
Affinity DataIC50: 8.60nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153366(CHEMBL3774467 | US9630914, Example 5)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153445(CHEMBL3775280 | US9630914, Example 15)copy SMILEScopy InChI
Affinity DataIC50: 9.10nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)copy SMILEScopy InChI
Affinity DataIC50: 9.90nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Universita` degli Studi di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human CYP11B1 expressed in Chinese hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone/11-deoxycorticosteroneMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153379(CHEMBL3775979 | US9630914, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153373(CHEMBL3774805 | US9630914, Example 9)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153446(CHEMBL3775770 | US9630914, Example 16)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153366(CHEMBL3774467 | US9630914, Example 5)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153377(CHEMBL3775104 | US9630914, Example 11)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153372(CHEMBL3774586 | US9630914, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153373(CHEMBL3774805 | US9630914, Example 9)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Universit£ di Bari

Curated by ChEMBL
LigandPNGBDBM50422877(CHEMBL213286)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondria MAOB by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4K1NPubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Universit£ di Bari

Curated by ChEMBL
LigandPNGBDBM50422872(CHEMBL213285)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondria MAOB by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4K1NPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153442(CHEMBL3774442 | US9630914, Example 18)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Universit£ di Bari

Curated by ChEMBL
LigandPNGBDBM50422878(CHEMBL211425)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondria MAOB by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4K1NPubMed
TargetAromatase(Homo sapiens (Human))
Universita` degli Studi di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50339655(7-(3,4-Difluorophenoxy)-4-(1H-imidazol-1-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X583QPubMed
TargetAromatase(Homo sapiens (Human))
Universita` degli Studi di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM9475(4-(1H-Imidazol-1-ylmethyl)-7-phenoxy-2H-chromen-2-...)copy SMILEScopy InChI
Affinity DataIC50: 51nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R0CPubMed
TargetAromatase(Homo sapiens (Human))
Universita` degli Studi di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM9475(4-(1H-Imidazol-1-ylmethyl)-7-phenoxy-2H-chromen-2-...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X583QPubMed
TargetAromatase(Homo sapiens (Human))
Universita` degli Studi di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X583QPubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153446(CHEMBL3775770 | US9630914, Example 16)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetAromatase(Homo sapiens (Human))
Universita` degli Studi di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50339659(CHEMBL1688915 | rac-4-[1H-Imidazol-1-yl(phenyl)met...)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X583QPubMed
TargetAromatase(Homo sapiens (Human))
Universita` degli Studi di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50339654(7-(3,5-Difluorophenoxy)-4-(1H-imidazol-1-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X583QPubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153371(CHEMBL3775973 | US9630914, Example 7)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Universit£ di Bari

Curated by ChEMBL
LigandPNGBDBM50422872(CHEMBL213285)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondria MAOB by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4K1NPubMed
TargetAromatase(Homo sapiens (Human))
Universita` degli Studi di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50339647(7-(3-Chlorophenoxy)-4-(1H-imidazol-1-ylmethyl)-2H-...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X583QPubMed
TargetAromatase(Homo sapiens (Human))
Universita` degli Studi di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50339646(7-(3-Fluorophenoxy)-4-(1H-imidazol-1-ylmethyl)-2H-...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X583QPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Universita` degli Studi di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM9485(7-(benzyloxy)-4-(1H-imidazol-1-ylmethyl)-2H-chrome...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of human CYP11B1 expressed in Chinese hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone/11-deoxycorticosteroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X583QPubMed
TargetAromatase(Homo sapiens (Human))
Universita` degli Studi di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM9465(1-(9-Phenyl-9H-fluoren-9-yl)-1H-imidazole | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 74nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R0CPubMed
TargetAromatase(Homo sapiens (Human))
Universita` degli Studi di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50339653(7-[4-(Dimethylamino)phenoxy]-4-(1H-imidazol-1-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X583QPubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153372(CHEMBL3774586 | US9630914, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna

US Patent
LigandPNGBDBM50153377(CHEMBL3775104 | US9630914, Example 11)copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H0SUS Patent
TargetAromatase(Homo sapiens (Human))
Universita` degli Studi di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50339656(7-Anilino-4-(1H-imidazol-1-ylmethyl)-2H-chromen-2-...)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X583QPubMed
TargetAromatase(Homo sapiens (Human))
Universita` degli Studi di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM9483(3-(1H-Imidazol-1-ylmethyl)-7-methoxy-4-phenyl-2H-c...)copy SMILEScopy InChI
Affinity DataIC50: 106nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R0CPubMed
Displayed 1 to 50 (of 341 total ) | Next | Last >>
Jump to: