Compile Data Set for Download or QSAR
Found 42 with Last Name = 'fejzic' and Initial = 'a'
TargetCannabinoid receptor 1(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

LigandPNGBDBM29100(dibenzothiazepine, 12h)copy SMILEScopy InChI
Affinity DataKi:  0.200nM ΔG°:  -54.8kJ/molepH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TFPPubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

LigandPNGBDBM29098(dibenzothiazepine, 12e)copy SMILEScopy InChI
Affinity DataKi:  0.200nM ΔG°:  -54.8kJ/molepH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TFPPubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

LigandPNGBDBM29096(dibenzothiazepine, 12b)copy SMILEScopy InChI
Affinity DataKi:  0.320nM ΔG°:  -53.6kJ/molepH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TFPPubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

LigandPNGBDBM29097(dibenzothiazepine, 12c)copy SMILEScopy InChI
Affinity DataKi:  0.790nM ΔG°:  -51.4kJ/molepH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TFPPubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

LigandPNGBDBM29101(dibenzothiazepine, 12j)copy SMILEScopy InChI
Affinity DataKi:  1.20nM ΔG°:  -50.4kJ/molepH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TFPPubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

LigandPNGBDBM29102(dibenzothiazepine, 12k)copy SMILEScopy InChI
Affinity DataKi:  1.60nM ΔG°:  -49.7kJ/molepH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TFPPubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)copy SMILEScopy InChI
Affinity DataKi:  2nM ΔG°:  -49.2kJ/molepH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TFPPubMedDrugBank
TargetCannabinoid receptor 1(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

LigandPNGBDBM29095(dibenzothiazepine, 12a)copy SMILEScopy InChI
Affinity DataKi:  3nM ΔG°:  -48.2kJ/molepH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TFPPubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

LigandPNGBDBM29094((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)copy SMILEScopy InChI
Affinity DataKi:  3nM ΔG°:  -48.2kJ/molepH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TFPPubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

LigandPNGBDBM29099(dibenzothiazepine, 12g)copy SMILEScopy InChI
Affinity DataKi:  25nM ΔG°:  -43.0kJ/molepH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TFPPubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

LigandPNGBDBM29103(dibenzothiazepine, 13)copy SMILEScopy InChI
Affinity DataKi:  40nM ΔG°:  -41.8kJ/molepH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TFPPubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)copy SMILEScopy InChI
Affinity DataKi:  398nM ΔG°:  -36.2kJ/molepH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TFPPubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

LigandPNGBDBM29100(dibenzothiazepine, 12h)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nM ΔG°:  -33.9kJ/molepH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TFPPubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

LigandPNGBDBM29097(dibenzothiazepine, 12c)copy SMILEScopy InChI
Affinity DataKi:  1.26E+3nM ΔG°:  -33.3kJ/molepH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TFPPubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

LigandPNGBDBM29094((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nM ΔG°:  -32.2kJ/molepH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TFPPubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

LigandPNGBDBM29099(dibenzothiazepine, 12g)copy SMILEScopy InChI
Affinity DataKi:  5.01E+3nM ΔG°:  -29.9kJ/molepH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TFPPubMed
TargetAndrogen receptor(Mus musculus)
ACADIA Pharmaceuticals AB

Curated by ChEMBL
LigandPNGBDBM50415093(CHEMBL570463)copy SMILEScopy InChI
Affinity DataEC50:  2nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MV9PubMed
TargetAndrogen receptor(Mus musculus)
ACADIA Pharmaceuticals AB

Curated by ChEMBL
LigandPNGBDBM50415094(CHEMBL578199)copy SMILEScopy InChI
Affinity DataEC50:  2nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MV9PubMed
TargetAndrogen receptor(Mus musculus)
ACADIA Pharmaceuticals AB

Curated by ChEMBL
LigandPNGBDBM50415095(CHEMBL568786)copy SMILEScopy InChI
Affinity DataEC50:  2nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MV9PubMed
TargetAndrogen receptor(Mus musculus)
ACADIA Pharmaceuticals AB

Curated by ChEMBL
LigandPNGBDBM50258791(4-(3-exo-Hydroxy-8-azabicyclo[3.2.1]oct-8-yl)napht...)copy SMILEScopy InChI
Affinity DataEC50:  100nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MV9PubMed
TargetAndrogen receptor(Mus musculus)
ACADIA Pharmaceuticals AB

Curated by ChEMBL
LigandPNGBDBM50415096(CHEMBL568814)copy SMILEScopy InChI
Affinity DataEC50:  3.98nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MV9PubMed
TargetAndrogen receptor(Mus musculus)
ACADIA Pharmaceuticals AB

Curated by ChEMBL
LigandPNGBDBM50415097(CHEMBL570897)copy SMILEScopy InChI
Affinity DataEC50:  6.31nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MV9PubMed
TargetAndrogen receptor(Mus musculus)
ACADIA Pharmaceuticals AB

Curated by ChEMBL
LigandPNGBDBM50415098(CHEMBL570898)copy SMILEScopy InChI
Affinity DataEC50:  15.8nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MV9PubMed
TargetAndrogen receptor(Mus musculus)
ACADIA Pharmaceuticals AB

Curated by ChEMBL
LigandPNGBDBM50415099(CHEMBL569985)copy SMILEScopy InChI
Affinity DataEC50:  15.8nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MV9PubMed
TargetAndrogen receptor(Mus musculus)
ACADIA Pharmaceuticals AB

Curated by ChEMBL
LigandPNGBDBM50415100(CHEMBL570413)copy SMILEScopy InChI
Affinity DataEC50:  5.01nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MV9PubMed
TargetAndrogen receptor(Mus musculus)
ACADIA Pharmaceuticals AB

Curated by ChEMBL
LigandPNGBDBM50415092(CHEMBL570895)copy SMILEScopy InChI
Affinity DataEC50:  2nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MV9PubMed
TargetAndrogen receptor(Mus musculus)
ACADIA Pharmaceuticals AB

Curated by ChEMBL
LigandPNGBDBM50415091(CHEMBL576474)copy SMILEScopy InChI
Affinity DataEC50:  12.6nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MV9PubMed
TargetAndrogen receptor(Mus musculus)
ACADIA Pharmaceuticals AB

Curated by ChEMBL
LigandPNGBDBM18161((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)copy SMILEScopy InChI
Affinity DataEC50:  3.98nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
TargetAndrogen receptor(Mus musculus)
ACADIA Pharmaceuticals AB

Curated by ChEMBL
LigandPNGBDBM8885((1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethylte...)copy SMILEScopy InChI
Affinity DataEC50:  2nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
TargetAndrogen receptor(Mus musculus)
ACADIA Pharmaceuticals AB

Curated by ChEMBL
LigandPNGBDBM50415090(CHEMBL576275)copy SMILEScopy InChI
Affinity DataEC50:  100nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MV9PubMed
TargetAndrogen receptor(Mus musculus)
ACADIA Pharmaceuticals AB

Curated by ChEMBL
LigandPNGBDBM50415089(CHEMBL570410)copy SMILEScopy InChI
Affinity DataEC50:  19.9nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MV9PubMed
TargetAndrogen receptor(Mus musculus)
ACADIA Pharmaceuticals AB

Curated by ChEMBL
LigandPNGBDBM50415088(CHEMBL577196)copy SMILEScopy InChI
Affinity DataEC50:  12.6nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MV9PubMed
TargetAndrogen receptor(Mus musculus)
ACADIA Pharmaceuticals AB

Curated by ChEMBL
LigandPNGBDBM50415087(CHEMBL570237)copy SMILEScopy InChI
Affinity DataEC50:  3.98nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MV9PubMed
TargetAndrogen receptor(Mus musculus)
ACADIA Pharmaceuticals AB

Curated by ChEMBL
LigandPNGBDBM50415086(ACP-105 | CHEMBL570435)copy SMILEScopy InChI
Affinity DataEC50:  1nMAssay Description:Agonist activity at androgen receptor in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MV9PubMed
TargetAndrogen receptor(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

Curated by ChEMBL
LigandPNGBDBM8885((1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethylte...)copy SMILEScopy InChI
Affinity DataEC50:  3.16nMAssay Description:Agonist activity at androgen receptor in human MDA-KB2 cells transfected with MMTV linked luciferase assessed as transcriptional activation by lucife...More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

Curated by ChEMBL
LigandPNGBDBM50415086(ACP-105 | CHEMBL570435)copy SMILEScopy InChI
Affinity DataEC50:  0.251nMAssay Description:Agonist activity at androgen receptor in human MDA-KB2 cells transfected with MMTV linked luciferase assessed as transcriptional activation by lucife...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MV9PubMed
TargetAndrogen receptor(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

Curated by ChEMBL
LigandPNGBDBM50415088(CHEMBL577196)copy SMILEScopy InChI
Affinity DataEC50:  1.58nMAssay Description:Agonist activity at androgen receptor in human MDA-KB2 cells transfected with MMTV linked luciferase assessed as transcriptional activation by lucife...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MV9PubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

LigandPNGBDBM29096(dibenzothiazepine, 12b)copy SMILEScopy InChI
Affinity DatapH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TFPPubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

LigandPNGBDBM29095(dibenzothiazepine, 12a)copy SMILEScopy InChI
Affinity DatapH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TFPPubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

LigandPNGBDBM29102(dibenzothiazepine, 12k)copy SMILEScopy InChI
Affinity DatapH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TFPPubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

LigandPNGBDBM29101(dibenzothiazepine, 12j)copy SMILEScopy InChI
Affinity DatapH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TFPPubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
ACADIA Pharmaceuticals AB

LigandPNGBDBM29098(dibenzothiazepine, 12e)copy SMILEScopy InChI
Affinity DatapH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TFPPubMed