Compile Data Set for Download or QSAR
Found 136 with Last Name = 'fekete' and Initial = 'a'
Target3-oxoacyl-[acyl-carrier-protein] synthase 1 [C171Q](Mycobacterium tuberculosis)
University of Wuerzburg

LigandPNGBDBM214777(TLM18)copy SMILEScopy InChI
Affinity DataKi:  3.84E+5nMpH: 8.5Assay Description:Binding of TLM18 to wild-type and mutant KasA was quantified by monitoring changes in the intrinsic tryptophan fluorescence of the enzyme at waveleng...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50169743((13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pe...)copy SMILEScopy InChI
Affinity DataIC50: 0.0600nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as inhibition of insulin-mediated cell proliferation after 6 days by Hoechst 33258 dye-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50237304(CHEMBL4093325)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:In vitro binding affinity at human cloned dopamine receptor D2 (short) stably expressed in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50237322(CHEMBL4088736)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 18 to 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50237317(CHEMBL4098286)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 18 to 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50237305(CHEMBL4072611)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Affinity of compound for Dopamine receptor D2 in rat striatal membrane determined for antagonist state (low affinity state, D2 Low) with [3H]spiperon...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50237332(CHEMBL4078937)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 18 to 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50237306(CHEMBL4076352)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 18 to 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50237302(CHEMBL4101697)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 18 to 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50169743((13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pe...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350831(CHEMBL1819273)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N24DWPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350832(CHEMBL1819274)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N24DWPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50169743((13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pe...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 18 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350818(CHEMBL1819257)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N24DWPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50237303(CHEMBL4065632)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 18 to 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350827(CHEMBL1819267)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N24DWPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50237302(CHEMBL4101697)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 18 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350835(CHEMBL1819272)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N24DWPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350820(CHEMBL1819260)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N24DWPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50237302(CHEMBL4101697)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as inhibition of insulin-mediated cell proliferation after 6 days by Hoechst 33258 dye-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50237320(CHEMBL4069539)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 18 to 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM20608(4-Hydroxytamoxifen | 4-Hydroxytamoxifen (9) | 4-[(...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Antagonist activity at ERalpha in human MCF7 cells assessed as inhibition of estrogen-induced transcription preincubated overnight followed by estrog...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350833(CHEMBL1819275)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N24DWPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM20593(2-(4-fluorophenyl)-1-methyl-1-{4-[2-(piperidin-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Antagonist activity at ERalpha in human MCF7 cells assessed as inhibition of estrogen-induced transcription preincubated overnight followed by estrog...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350830(CHEMBL1819270)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N24DWPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50169743((13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pe...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Antagonist activity at ERalpha in human MCF7 cells assessed as inhibition of estrogen-induced transcription preincubated overnight followed by estrog...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350821(CHEMBL1819261)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N24DWPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50237329(CHEMBL4090556)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 18 to 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350826(CHEMBL1819266)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N24DWPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50237328(CHEMBL4087804)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 18 to 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350838(CHEMBL1819271)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N24DWPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350829(CHEMBL1819269)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N24DWPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50237332(CHEMBL4078937)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Antagonist activity at ERalpha in human MCF7 cells assessed as inhibition of estrogen-induced transcription preincubated overnight followed by estrog...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50084948(CHEMBL195515 | GW7604)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50237299(CHEMBL4063001)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 18 to 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50237322(CHEMBL4088736)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350824(CHEMBL1819264)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N24DWPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350828(CHEMBL1819268)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N24DWPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50237306(CHEMBL4076352)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Antagonist activity at ERalpha in human MCF7 cells assessed as inhibition of estrogen-induced transcription preincubated overnight followed by estrog...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350822(CHEMBL1819262)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N24DWPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350817(CHEMBL1819256)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N24DWPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50237307(CHEMBL4087134)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibitory concentration against Protein-tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350816(CHEMBL1819255)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N24DWPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350813(CHEMBL1819141)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N24DWPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350810(CHEMBL1819138)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N24DWPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N24DWPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50237301(CHEMBL4083087)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 18 to 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50134232((E)-N-Hydroxy-3-(4-{[2-(1H-indol-3-yl)-ethylamino]...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N24DWPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50237319(CHEMBL4080245)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 18 to 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB845QPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350834(CHEMBL1819259)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N24DWPubMed
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