Compile Data Set for Download or QSAR
Found 27 with Last Name = 'focella' and Initial = 'a'
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50009075(CHEMBL22033 | ICI 198615 | ICI-198615 | [1-(4-Benz...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory activity of the compound to inhibit Inophore-induced arachidonic acid metabolism (inhibition of TXB2 formation) in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibitory activity of the compound to inhibit Inophore-induced arachidonic acid metabolism (inhibition of TXB2 formation) in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50228307(CGP-35949)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50000838(CHEMBL416657 | Sodium; 3-[3-tert-butylsulfanyl-1-(...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity of the compound to inhibit Inophore-induced arachidonic acid metabolism (inhibition of TXB2 formation) in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50017208(6-Acetyl-7-[5-(4-acetyl-3-hydroxy-2-propyl-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity of compound to block binding of [3H]-leukotriene D4 to Cysteinyl leukotriene D4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50228313(CHEMBL55714)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50228304(CHEMBL417028)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50009071(6-Acetyl-7-[5-(4-acetyl-3-hydroxy-2-propyl-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity of compound to block binding of [3H]-leukotriene D4 to Cysteinyl leukotriene D4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50006812(7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50228311(CHEMBL53333)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50228301(CHEMBL54688)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50017202(6-Acetyl-7-[6-(4-acetyl-3-hydroxy-2-propyl-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity of compound to block binding of [3H]-leukotriene D4 to Cysteinyl leukotriene D4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50228300(CHEMBL293529)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50017201(6-Acetyl-7-[5-(4-acetyl-3-hydroxy-2-propyl-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Invitro activity of the compound to inhibit binding of [3H]- leukotriene D4 to receptor sites in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50228302(CHEMBL53512)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50009071(6-Acetyl-7-[5-(4-acetyl-3-hydroxy-2-propyl-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory activity of the compound to inhibit Inophore-induced arachidonic acid metabolism (inhibition of TXB2 formation) in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50006806(C,C,C-Trifluoro-N-[3-(quinolin-2-ylmethoxy)-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50017209(6-Acetyl-7-[3-(4-acetyl-3-hydroxy-2-propyl-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory activity of compound to block binding of [3H]-leukotriene D4 to Cysteinyl leukotriene D4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50228303(CHEMBL52877)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50017199(6-Acetyl-7-[3-(4-acetyl-3-hydroxy-2-propyl-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory activity of compound to block binding of [3H]-leukotriene D4 to Cysteinyl leukotriene D4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50017200(6-Acetyl-7-[5-(4-acetyl-3-hydroxy-2-propyl-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory activity of compound to block binding of [3H]-leukotriene D4 toCysteinyl leukotriene D4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50228306(CHEMBL55164)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:In vitro activity to inhibit binding of [3H]- leukotriene D4 to receptor sites in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
LigandPNGBDBM50009071(6-Acetyl-7-[5-(4-acetyl-3-hydroxy-2-propyl-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1AMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
LigandPNGBDBM50006812(7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1AMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
LigandPNGBDBM50017210(8-(1,2-Dimethyl-propyl)-purine-2,6-dione | CHEMBL5...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1AMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
LigandPNGBDBM10847(1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dion...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1AMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed