Compile Data Set for Download or QSAR
Found 365 with Last Name = 'ganesan' and Initial = 'a'
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of recombinant human C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in sf9 cells using acetyl-Lys(Ac)-AMC as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Inhibition of human C-terminal His-tagged HDAC3 (1 to 428 residues)/human N-terminal GST-tagged NcoR2 (395 to 489 residues) expressed in sf9 cells us...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMedDrugBank
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50155773(CHEMBL3781751 | US9469597, 5)copy SMILEScopy InChI
Affinity DataKi:  18nMMore data for this Ligand-Target Pair
In DepthDetails
TargetHistone deacetylase 9(Homo sapiens (Human))TBA
LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Inhibition of human HDAC9 using (Boc-Lys(trifluoroacetyl)-AMC) as substrate measured after 2 hrs by Cheng-Prusoff analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetHistone deacetylase 7(Homo sapiens (Human))TBA
LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataKi:  36nMAssay Description:Inhibition of human HDAC7 using (Boc-Lys(trifluoroacetyl)-AMC) as substrate measured after 2 hrs by Cheng-Prusoff analysisMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM113742(N-[4-(2-Hydrazinylethyl)phenyl]-4-phenylbutanamide...)copy SMILEScopy InChI
Affinity DataKi:  59nMMore data for this Ligand-Target Pair
In DepthDetails
TargetHistone deacetylase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataKi:  80nMAssay Description:Inhibition of human HDAC5 using (Boc-Lys(trifluoroacetyl)-AMC) as substrate measured after 2 hrs by Cheng-Prusoff analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataKi:  126nMAssay Description:Inhibition of human HDAC4 using (Boc-Lys(trifluoroacetyl)-AMC) as substrate measured after 2 hrs by Cheng-Prusoff analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM207628(US9265734, RGFA8 | US9796664, Compound RGFA8)copy SMILEScopy InChI
Affinity DataKi:  148nMAssay Description:Inhibition of recombinant human C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in sf9 cells using acetyl-Lys(Ac)-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50565137(CHEMBL4800126)copy SMILES
Affinity DataKi:  370nMAssay Description:Inhibition of human HDAC2 expressed in Sf9 cells using Ac-Leu-Gly-Lys(Ac)-AMC as substrate measured every 30 secs for 60 mins by fluorescence-based a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50565137(CHEMBL4800126)copy SMILES
Affinity DataKi:  690nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-Leu-Gly-Lys(Ac)-AMC as substrate measured every 30 secs for 60 mins by fluorescence-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
LigandPNGBDBM50565137(CHEMBL4800126)copy SMILES
Affinity DataKi:  800nMAssay Description:Inhibition of human C-terminal His-tagged HDAC3 (1 to 428 residues)/human N-terminal GST-tagged NcoR2 (395 to 489 residues) expressed in sf9 cells us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50346586(CHEMBL1795981 | US8765820, 5a)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human LSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50346585(CHEMBL1795980 | S2101)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human LSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50346584(CHEMBL1795979)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human LSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))TBA
LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human HDAC6 using p53 residues 379-382 (RHKKAc) as substrate measured after 2 hrs by Cheng-Prusoff analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50346589(CHEMBL1795974 | CHEMBL255520)copy SMILEScopy InChI
Affinity DataKi:  3.70E+3nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of human HDAC8 using p53 residues 379-382 (RHKAcKAc) as substrate as substrate measured after 2 hrs by Cheng-Prusoff analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50346583(CHEMBL1795978)copy SMILEScopy InChI
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of human LSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50105417(CHEMBL1089 | Nardil | PHENELZINE | Phenethyl-hydra...)copy SMILEScopy InChI
Affinity DataKi:  6.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50346591(CHEMBL1795982)copy SMILEScopy InChI
Affinity DataKi:  6.80E+3nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50346582(CHEMBL1795977)copy SMILEScopy InChI
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of human LSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50346590(CHEMBL1795975)copy SMILEScopy InChI
Affinity DataKi:  8.90E+3nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50346594(CHEMBL1795976)copy SMILEScopy InChI
Affinity DataKi:  1.17E+4nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataKi: >1.90E+4nMAssay Description:Inhibition of human HDAC2 using p53 (379 to 382 residues) (RHKKAc) as substrate measured after 2 hrs by Cheng-Prusoff analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetHistone deacetylase 11(Homo sapiens (Human))TBA
LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataKi: >1.90E+4nMAssay Description:Inhibition of human HDAC11 using (Boc-Lys(trifluoroacetyl)-AMC) as substrate measured after 2 hrs by Cheng-Prusoff analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50240772((1R,2S)-(-)-2-phenylcyclopropylamine | (1R,2S)-2-p...)copy SMILEScopy InChI
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of human LSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataKi: >2.30E+4nMAssay Description:Inhibition of human HDAC1 using p53 (379 to 382 residues) (RHKKAc) as substrate measured after 2 hrs by cheng-Prusoff analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50113851((+/-)-Tranylcypromine | 2-PCPA | 2-Phenyl-cyclopro...)copy SMILEScopy InChI
Affinity DataKi:  2.50E+4nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50240772((1R,2S)-(-)-2-phenylcyclopropylamine | (1R,2S)-2-p...)copy SMILEScopy InChI
Affinity DataKi:  2.50E+4nMMore data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50236898((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...)copy SMILEScopy InChI
Affinity DataKi:  2.66E+4nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50236898((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...)copy SMILEScopy InChI
Affinity DataKi:  2.81E+4nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50346587(CHEMBL1795972)copy SMILEScopy InChI
Affinity DataKi:  4.18E+4nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataKi: >4.30E+4nMAssay Description:Inhibition of human HDAC3/NcoR2 using p53 residues 379-382 (RHKKAc) as substrate measured after 2 hrs by Cheng-Prusoff analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50346588(CHEMBL1795973)copy SMILEScopy InChI
Affinity DataKi:  7.96E+4nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50346593(CHEMBL1795984)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50346592(CHEMBL1795983)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50236898((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...)copy SMILEScopy InChI
Affinity DataKi:  1.68E+5nMAssay Description:Inhibition of human truncated LSD1 lacking N-terminal 184 amino acidsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50236898((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...)copy SMILEScopy InChI
Affinity DataKi:  1.68E+5nMAssay Description:Inhibition of human truncated LSD1 lacking N-terminal 184 amino acidsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human HDAC1 expressed in baculovirus infected sf9 cells using p53 residues 379-382 (RHKKAc) as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant human HDAC1 using pan-HDAC substrate incubated for 3 hrs by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human HDAC2 expressed in baculovirus infected sf9 cells using p53 residues 379-382 (RHKKAc) as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetHistone deacetylase 11(Homo sapiens (Human))TBA
LigandPNGBDBM50048864(CHEMBL3310505)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetHistone deacetylase 11(Homo sapiens (Human))TBA
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human HDAC11 expressed in baculovirus infected sf9 cells using (Boc-Lys(trifluoroacetyl)-AMC) as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))TBA
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetHistone deacetylase 9(Homo sapiens (Human))TBA
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant human HDAC9 using pan-HDAC substrate incubated for 3 hrs by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human HDAC4 expressed in baculovirus infected sf9 cells using (Boc-Lys(trifluoroacetyl)-AMC) as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetAcid ceramidase(Homo sapiens (Human))
Istituto Italiano di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50238556(CHEMBL4093029)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of 5-HT uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB481GPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))TBA
LigandPNGBDBM50048864(CHEMBL3310505)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
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